scholarly journals Cytolytic Pathways Used by Effector Cells Derived from Recipient Naive and Memory T Cells and Natural Killer Cells in Resistance to Allogeneic Hematopoietic Cell Transplantation

2005 ◽  
Vol 11 (12) ◽  
pp. 957-971 ◽  
Author(s):  
Zachary Zimmerman ◽  
Monica Jones ◽  
Alwi Shatry ◽  
Masanobu Komatsu ◽  
Michele Mammolenti ◽  
...  
Keyword(s):  
T Cells ◽  
Natural Killer Cells ◽  
Natural Killer ◽  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
Memory T Cells ◽  
Hematopoietic Cell ◽  
Allogeneic Hematopoietic Cell Transplantation ◽  
Killer Cells ◽  
Effector Cells

scholarly journals Infusion of donor-derived CD8+ memory T cells for relapse following allogeneic hematopoietic cell transplantation

2018 ◽  
Vol 2 (6) ◽  
pp. 681-690 ◽  
Author(s):  
Lori Muffly ◽  
Kevin Sheehan ◽  
Randall Armstrong ◽  
Kent Jensen ◽  
Keri Tate ◽  
...  
Keyword(s):  
T Cells ◽  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
Memory T Cells ◽  
Hematopoietic Cell ◽  
Allogeneic Hematopoietic Cell Transplantation ◽  
Allogeneic Hct ◽  
Key Points ◽  
Cd8 Memory T Cells

Key Points Phenotypic TM isolation from unmanipulated donor apheresis via CD45RA depletion followed by CD8+ enrichment is feasible. TM infusion for patients with relapse after allogeneic HCT was safe and resulted in minimal GVHD.

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