scholarly journals Analysis of Single Nucleotide Polymorphisms (SNP) Donor/Recipient Mismatches in the Gamma Block of the Major Histocompatibility Complex (MHC) and Their Association with Hematopoietic Cell Transplantation (HCT) Outcomes: A CIBMTR Study

2018 ◽  
Vol 24 (3) ◽  
pp. S417-S418 ◽  
Author(s):  
Medhat Askar ◽  
David Sayer ◽  
Tao Wang ◽  
Michael Haagenson ◽  
Stephen R. Spellman ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Single Nucleotide Polymorphisms ◽  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
Hematopoietic Cell ◽  
Nucleotide Polymorphisms ◽  
Major Histocompatibility ◽  
Single Nucleotide ◽  
Histocompatibility Complex

scholarly journals Validation of single nucleotide polymorphisms in invasive aspergillosis following hematopoietic cell transplantation

Blood ◽  
2017 ◽  
Vol 129 (19) ◽  
pp. 2693-2701 ◽  
Author(s):  
Cynthia E. Fisher ◽  
Tobias M. Hohl ◽  
Wenhong Fan ◽  
Barry E. Storer ◽  
David M. Levine ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Invasive Aspergillosis ◽  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
Genetic Model ◽  
Original Study ◽  
Hematopoietic Cell ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Key Points

Key Points Two SNPs in PTX3 and CLEC7a previously associated with development of proven or probable invasive aspergillosis were validated. Thirteen SNPs in 9 genes were associated at P ≤ .05 with development of IA using a different genetic model than the original study.

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