scholarly journals Incidence of Anicteric Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome and Outcomes with Defibrotide following Hematopoietic Cell Transplantation in Adult and Pediatric Patients

2020 ◽  
Vol 26 (7) ◽  
pp. 1342-1349 ◽  
Author(s):  
Selim Corbacioglu ◽  
Nancy A. Kernan ◽  
Antonio Pagliuca ◽  
Robert J. Ryan ◽  
William Tappe ◽  
...  
Keyword(s):  
Cell Transplantation ◽  
Pediatric Patients ◽  
Hematopoietic Cell Transplantation ◽  
Occlusive Disease ◽  
Hematopoietic Cell ◽  
Sinusoidal Obstruction Syndrome

How I treat sinusoidal obstruction syndrome

Blood ◽  
2014 ◽  
Vol 123 (26) ◽  
pp. 4023-4026 ◽  
Author(s):  
Nelson Chao
Keyword(s):  
Supportive Care ◽  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
Difficult Problem ◽  
Occlusive Disease ◽  
Hematopoietic Cell ◽  
Sinusoidal Obstruction Syndrome ◽  
Allogeneic Hct

AbstractSinusoidal obstruction syndrome (SOS), previously called veno-occlusive disease (VOD) can be a difficult problem after hematopoietic cell transplantation (HCT). The overall incidence has changed since the early days of allogeneic HCT. Prophylaxis and treatment remain important components of supportive care. As the indication and the comorbidities for HCT continue to change, especially with older and more infirm patients, SOS remains an important area for clinicians. I discuss how SOS could be addressed, from prophylaxis to diagnosis and potential therapy.

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