scholarly journals PF747 DEFIBROTIDE TREATMENT IN ADULTS WITH SEVERE OR VERY SEVERE VENO-OCCLUSIVE DISEASE/SINUSOIDAL OBSTRUCTION SYNDROME AFTER HEMATOPOIETIC CELL TRANSPLANTATION: DEFIFRANCE STUDY INTERIM RESULTS

HemaSphere ◽  
2019 ◽  
Vol 3 (S1) ◽  
pp. 327-328
Author(s):  
I. Yakoub-Agha ◽  
M. Labopin ◽  
D. Blaise ◽  
R. Peffault de Latour ◽  
V. Bouvatier ◽  
...  
Keyword(s):  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
Occlusive Disease ◽  
Hematopoietic Cell ◽  
Sinusoidal Obstruction Syndrome

How I treat sinusoidal obstruction syndrome

Blood ◽  
2014 ◽  
Vol 123 (26) ◽  
pp. 4023-4026 ◽  
Author(s):  
Nelson Chao
Keyword(s):  
Supportive Care ◽  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
Difficult Problem ◽  
Occlusive Disease ◽  
Hematopoietic Cell ◽  
Sinusoidal Obstruction Syndrome ◽  
Allogeneic Hct

AbstractSinusoidal obstruction syndrome (SOS), previously called veno-occlusive disease (VOD) can be a difficult problem after hematopoietic cell transplantation (HCT). The overall incidence has changed since the early days of allogeneic HCT. Prophylaxis and treatment remain important components of supportive care. As the indication and the comorbidities for HCT continue to change, especially with older and more infirm patients, SOS remains an important area for clinicians. I discuss how SOS could be addressed, from prophylaxis to diagnosis and potential therapy.

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