Effects of chemical stimulation of the lateral wings of the dorsal raphe nucleus on panic-like defensive behaviors and Fos protein expression in rats

2017 ◽  
Vol 326 ◽  
pp. 103-111 ◽  
Author(s):  
Melina Matthiesen ◽  
Ailton Spiacci ◽  
Hélio Zangrossi
Keyword(s):  
Protein Expression ◽  
Dorsal Raphe Nucleus ◽  
Dorsal Raphe ◽  
Chemical Stimulation ◽  
Raphe Nucleus ◽  
Fos Protein ◽  
Defensive Behaviors ◽  
Dorsal Raphé ◽  
Stimulation Of

Effect of chemical stimulation of the dorsal raphe nucleus on cerebral blood flow in rat

1995 ◽  
Vol 199 (3) ◽  
pp. 228-230 ◽  
Author(s):  
Mark D. Underwood ◽  
Mihran J. Bakalian ◽  
Victoria Arango ◽  
J. John Mann
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Dorsal Raphe Nucleus ◽  
Dorsal Raphe ◽  
Chemical Stimulation ◽  
Raphe Nucleus ◽  
Dorsal Raphé ◽  
Stimulation Of

scholarly journals Differential Effects of Electrical Stimulation of the Dorsal Raphe Nucleus and of Cervical Sympathectomy on Serotonin and Noradrenaline Concentrations in Major Cerebral Arteries and Pial Vessels in the Rat

1990 ◽  
Vol 10 (1) ◽  
pp. 123-126 ◽  
Author(s):  
G. Bonvento ◽  
P. Lacombe ◽  
E. T. MacKenzie ◽  
L. Rouquier ◽  
B. Scatton ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Dorsal Raphe Nucleus ◽  
Cerebral Arteries ◽  
Dorsal Raphe ◽  
Raphe Nucleus ◽  
Cervical Sympathectomy ◽  
Large Arteries ◽  
Pial Vessels ◽  
Dorsal Raphé ◽  
Stimulation Of

The levels of noradrenaline (NA), serotonin (5-HT), and 5-hydroxyindoleacetic acid were measured by HPLC and compared between the large arteries of the circle of Willis and the small pial vessels in the rat, following either electrical stimulation of the dorsal raphe nucleus or bilateral superior cervical ganglionectomy. With electrical stimulation, the 5-HT concentrations were reduced (– 48%) in the small pial vessels, but were unchanged in the major cerebral arteries. NA concentrations were dramatically reduced following cervical sympathectomy in the large arteries (– 77%), though the reduction was less pronounced (– 34%) in the small vessels. Sympathectomy caused a significant decrease in the 5-HT concentration of the major cerebral arteries (–33%), but was without effect on the 5-HT levels of the small pial vessels. These results show that an appreciable fraction of the perivascular 5-HT measured in the small pial and the large cerebral arteries originates from different sources.

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