Positive allosteric modulators of alpha 7 nicotinic acetylcholine receptors enhance procognitive effects of conventional anti-Alzheimer drugs in scopolamine-treated rats

Acetylcholine Receptors ◽

Allosteric Modulators ◽

Nicotinic Acetylcholine ◽

Positive Allosteric Modulators ◽

Alpha 7

Positive allosteric modulators of alpha 7 nicotinic acetylcholine receptors reverse ketamine-induced schizophrenia-like deficits in rats

Neuropharmacology ◽

10.1016/j.neuropharm.2015.07.034 ◽

2016 ◽

Vol 101 ◽

pp. 389-400 ◽

Cited By ~ 32

Author(s):

Agnieszka Nikiforuk ◽

Tomasz Kos ◽

Małgorzata Hołuj ◽

Agnieszka Potasiewicz ◽

Piotr Popik

Keyword(s):

Acetylcholine Receptors ◽

Allosteric Modulators ◽

Nicotinic Acetylcholine ◽

Positive Allosteric Modulators ◽

Alpha 7

Macroscopic and Microscopic Activation of α7 Nicotinic Acetylcholine Receptors by the Structurally Unrelated Allosteric Agonist-Positive Allosteric Modulators (ago-PAMs) B-973B and GAT107

Molecular Pharmacology ◽

10.1124/mol.118.113340 ◽

2018 ◽

Vol 95 (1) ◽

pp. 43-61 ◽

Cited By ~ 9

Author(s):

Marta Quadri ◽

Sumanta Garai ◽

Ganesh A. Thakur ◽

Clare Stokes ◽

Alican Gulsevin ◽

...

Keyword(s):

Acetylcholine Receptors ◽

Allosteric Modulators ◽

Nicotinic Acetylcholine ◽

Positive allosteric modulators of α7* or β2* nicotinic acetylcholine receptors trigger different kinase pathways in mitochondria

The International Journal of Biochemistry & Cell Biology ◽

10.1016/j.biocel.2018.04.018 ◽

2018 ◽

Vol 99 ◽

pp. 226-235 ◽

Cited By ~ 5

Author(s):

Kateryna Uspenska ◽

Olena Lykhmus ◽

Hugo R. Arias ◽

Stephanie Pons ◽

Uwe Maskos ◽

...

Keyword(s):

Acetylcholine Receptors ◽

Allosteric Modulators ◽

Nicotinic Acetylcholine ◽

Synthesis and activity of substituted heteroaromatics as positive allosteric modulators for α4β2α5 nicotinic acetylcholine receptors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2013.11.049 ◽

2014 ◽

Vol 24 (2) ◽

pp. 674-678 ◽

Cited By ~ 10

Author(s):

Zhuang Jin ◽

Pasha Khan ◽

Youseung Shin ◽

Jingyi Wang ◽

Li Lin ◽

...

Keyword(s):

Acetylcholine Receptors ◽

Allosteric Modulators ◽

Nicotinic Acetylcholine ◽

Chalcones as positive allosteric modulators of α7 nicotinic acetylcholine receptors: A new target for a privileged structure

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2014.09.039 ◽

2014 ◽

Vol 86 ◽

pp. 724-739 ◽

Cited By ~ 14

Author(s):

Beatriz Balsera ◽

José Mulet ◽

Asia Fernández-Carvajal ◽

Roberto de la Torre-Martínez ◽

Antonio Ferrer-Montiel ◽

...

Keyword(s):

Acetylcholine Receptors ◽

Allosteric Modulators ◽

Nicotinic Acetylcholine ◽

Privileged Structure ◽

Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content

The International Journal of Biochemistry & Cell Biology ◽

10.1016/j.biocel.2016.04.015 ◽

2016 ◽

Vol 76 ◽

pp. 19-30 ◽

Cited By ~ 9

Author(s):

Hugo R. Arias ◽

Federica Ravazzini ◽

Katarzyna M. Targowska-Duda ◽

Agnieszka A. Kaczor ◽

Dominik Feuerbach ◽

...

Keyword(s):

Ion Channels ◽

Acetylcholine Receptors ◽

Allosteric Modulators ◽

Nicotinic Acetylcholine ◽

Voltage Gated ◽

Β Amyloid ◽

Positive Allosteric Modulators ◽

Voltage Gated Ion Channels

Pharmacological Characterization of Natural Tobacco Alkaloids in the Presence of Positive Allosteric Modulators Against Human α4β2 and α7 Nicotinic Acetylcholine Receptors

Biophysical Journal ◽

10.1016/j.bpj.2019.11.790 ◽

2020 ◽

Vol 118 (3) ◽

pp. 119a

Author(s):

Omar Alijevic ◽

Damian Mc Hugh ◽

Anatoly Mazurov ◽

Julia Hoeng ◽

Manuel Peitsch

Keyword(s):

Acetylcholine Receptors ◽

Allosteric Modulators ◽

Pharmacological Characterization ◽

Nicotinic Acetylcholine ◽

Tobacco Alkaloids ◽

Design, Synthesis, and Functional Evaluation of a Novel Series of Phosphonate-Functionalized 1,2,3-Triazoles as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.0c00348 ◽

2020 ◽

Vol 11 (17) ◽

pp. 2688-2704

Author(s):

Beatriz Elizabeth Nielsen ◽

Santiago Stabile ◽

Cristian Vitale ◽

Cecilia Bouzat

Keyword(s):

Acetylcholine Receptors ◽

Functional Evaluation ◽

Allosteric Modulators ◽

Nicotinic Acetylcholine ◽

Design Synthesis ◽

Design and Synthesis of Novel Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors with the Ability To Rescue Auditory Gating Deficit in Mice

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.7b01492 ◽

2018 ◽

Vol 62 (1) ◽

pp. 159-173 ◽

Cited By ~ 3

Author(s):

Yuanheng Li ◽

Lilan Sun ◽

Taoyi Yang ◽

Wenxuan Jiao ◽

Jingshu Tang ◽

...

Keyword(s):

Acetylcholine Receptors ◽

Allosteric Modulators ◽

Nicotinic Acetylcholine ◽

Design And Synthesis ◽

Auditory Gating ◽

Characterization of type I and type II positive allosteric modulators of α7 nicotinic acetylcholine receptors

Biochemical Pharmacology ◽

10.1016/j.bcp.2009.06.067 ◽

2009 ◽

Vol 78 (7) ◽

pp. 914

Author(s):

Gareth T. Young ◽

Neil S. Millar

Keyword(s):

Acetylcholine Receptors ◽

Type I ◽

Allosteric Modulators ◽

Type Ii ◽

Nicotinic Acetylcholine ◽