Inhibition of adenine nucleotide transport in rat liver mitochondria by long-chain acyl-coenzyme A β-oxidation intermediates

2007 ◽  
Vol 352 (4) ◽  
pp. 873-878 ◽  
Author(s):  
Fátima V. Ventura ◽  
Isabel Tavares de Almeida ◽  
Ronald J.A. Wanders
1965 ◽  
Vol 97 (2) ◽  
pp. 587-594 ◽  
Author(s):  
PB Garland ◽  
D Shepherd ◽  
DW Yates

1. Fluorimetric assays are described for CoASH, acetyl-CoA and long-chain fatty acyl-CoA, and are sensitive to at least 50mumumoles of each. 2. Application of these assays to rat-liver mitochondria oxidizing palmitate in the absence and presence of carnitine indicated two pools of intramitochondrial CoA. One pool could be acylated by palmitate and ATP, and the other pool acylated by palmitate with ATP and carnitine, or by palmitoylcarnitine alone. 3. The intramitochondrial content of acetyl-CoA is increased by the oxidation of palmitate both in the absence and presence of l-malate. 4. The conversion of palmitoyl-CoA into acetyl-CoA by beta-oxidation takes place without detectable accumulation of acyl-CoA intermediates.


1967 ◽  
Vol 242 (9) ◽  
pp. 2111-2115 ◽  
Author(s):  
Lauro Galzigna ◽  
Carlo R. Rossi ◽  
Lodovico Sartorelli ◽  
David M. Gibson

1979 ◽  
Vol 98 (1) ◽  
pp. 165-172 ◽  
Author(s):  
Takao TANAKA ◽  
Kohei HOSAKA ◽  
Minoru HOSHIMARU ◽  
Shosaku NUMA

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