Current status and outlook of biodegradable metals in neuroscience and their potential applications as cerebral vascular stent materials

Liver disease is one of the leading causes of death worldwide, leading to the death of approximately 2 million people per year. Current therapies include orthotopic liver transplantation, however, donor organ shortage remains a great challenge. In addition, the development of novel therapeutics has been limited due to the lack of in vitro models that mimic in vivo liver physiology. Accordingly, hepatic cell lineages derived from human pluripotent stem cells (hPSCs) represent a promising cell source for liver cell therapy, disease modelling, and drug discovery. Moreover, the development of new culture systems bringing together the multiple liver-specific hepatic cell types triggered the development of hPSC-derived liver organoids. Therefore, these human liver-based platforms hold great potential for clinical applications. In this review, the production of the different hepatic cell lineages from hPSCs, including hepatocytes, as well as the emerging strategies to generate hPSC-derived liver organoids will be assessed, while current biomedical applications will be highlighted.

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Stem cell technology in breast cancer: current status and potential applications

Stem Cells and Cloning Advances and Applications ◽

10.2147/sccaa.s72836 ◽

2016 ◽

pp. 17 ◽

Cited By ~ 2

Author(s):

Panayiotis Theodoropoulos ◽

Rena Chiotaki ◽

Hara Polioudaki

Keyword(s):

Breast Cancer ◽

Stem Cell ◽

Current Status ◽

Stem Cell Technology ◽

Cell Technology ◽

Potential Applications

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To Analyze the Causes, Mechanisms and Preventive Methods of Complications after Cerebral Vascular Stent Implantation

10.47939/mh.v2i11.347 ◽

2021 ◽

Keyword(s):

Stent Implantation ◽

Vascular Stent ◽

Preventive Methods ◽

Cerebral Vascular

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Integrated POSS-dendrimer nanohybrid materials: current status and future perspective

Nanoscale ◽

10.1039/d0nr02394a ◽

2020 ◽

Vol 12 (21) ◽

pp. 11395-11415 ◽

Cited By ~ 5

Author(s):

Zhan Li ◽

Junfei Hu ◽

Lei Yang ◽

Xueqian Zhang ◽

Xianhu Liu ◽

...

Keyword(s):

Current Status ◽

Future Perspective ◽

Future Directions ◽

Current Trends ◽

Macroscopic Properties ◽

Potential Applications ◽

Nanohybrid Materials

This review summarizes POSS-dendrimer nanohybrid materials, focusing on their synthesis strategies, adjustable macroscopic properties, and potential applications. Moreover, their current trends, challenges and future directions are also elaborated.

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