Design, Synthesis and Molecular Docking Studies of Novel Indole-Pyrimidine Hybrids as Tubulin Polymerization Inhibitors

2015 ◽  
Vol 86 (6) ◽  
pp. 1491-1500 ◽  
Author(s):  
Meng-Jin Hu ◽  
Bei Zhang ◽  
Hai-Kui Yang ◽  
Yang Liu ◽  
Yu-Rong Chen ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Docking Studies ◽  
Tubulin Polymerization ◽  
Design Synthesis ◽  
Molecular Docking Studies ◽  
Tubulin Polymerization Inhibitors

Synthesis, biological evaluation, and molecular docking studies of novel chalcone oxime derivatives as potential tubulin polymerization inhibitors

RSC Advances ◽  
2014 ◽  
Vol 4 (61) ◽  
pp. 32263-32275 ◽  
Author(s):  
Yan-Ting Wang ◽  
Ya-Juan Qin ◽  
Ya-Liang Zhang ◽  
Yu-Jing Li ◽  
Bing Rao ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Cancer Cell ◽  
Inhibitory Activity ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Tubulin Polymerization ◽  
Molecular Docking Studies ◽  
Oxime Derivatives ◽  
Tubulin Polymerization Inhibitors

Compounds of novel chalcone oxime derivatives containing different substituent groups were designed, synthesized and evaluated for the inhibitory activity against tubulin polymerization and cancer cell inhibitory activity.

Indazoles as potential c-met inhibitors: Design, synthesis and molecular docking studies

2013 ◽  
Vol 65 ◽  
pp. 112-118 ◽  
Author(s):  
Lianbao Ye ◽  
Xiaomin Ou ◽  
Yuanxin Tian ◽  
Bangwei Yu ◽  
Yan Luo ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Docking Studies ◽  
Design Synthesis ◽  
Molecular Docking Studies
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