scholarly journals PSB 603 – a known selective adenosine A2B receptor antagonist – has anti-inflammatory activity in mice

2021 ◽  
Vol 135 ◽  
pp. 111164
Author(s):  
Magdalena Kotańska ◽  
Małgorzata Szafarz ◽  
Kamil Mika ◽  
Anna Dziubina ◽  
Marek Bednarski ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Inflammatory Activity ◽  
Adenosine A2b Receptor ◽  
A2b Receptor ◽  
Anti Inflammatory ◽  
Adenosine A2b

Potent antagonists for the human adenosine A2B receptor. Derivatives of the triazolotriazine adenosine receptor antagonist ZM241385 with high affinity

1999 ◽  
Vol 48 (3) ◽  
pp. 95-103 ◽  
Author(s):  
Maarten de Zwart ◽  
Roel C. Vollinga ◽  
Margot W. Beukers ◽  
Danielle F. Sleegers ◽  
Jacobien K. von Frijtag Drabbe K�nzel ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Adenosine Receptor ◽  
Adenosine A2b Receptor ◽  
Adenosine Receptor Antagonist ◽  
High Affinity ◽  
A2b Receptor ◽  
Derivatives Of ◽  
Adenosine A2b

Fluorescent-Labeled Selective Adenosine A2B Receptor Antagonist Enables Competition Binding Assay by Flow Cytometry

2018 ◽  
Vol 61 (10) ◽  
pp. 4301-4316 ◽  
Author(s):  
Meryem Köse ◽  
Sabrina Gollos ◽  
Tadeusz Karcz ◽  
Amelie Fiene ◽  
Fabian Heisig ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Receptor Antagonist ◽  
Binding Assay ◽  
Adenosine A2b Receptor ◽  
Competition Binding Assay ◽  
A2b Receptor ◽  
Competition Binding ◽  
Adenosine A2b

scholarly journals Elevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activity

Blood ◽  
2015 ◽  
Vol 125 (10) ◽  
pp. 1643-1652 ◽  
Author(s):  
Kaiqi Sun ◽  
Yujin Zhang ◽  
Mikhail V. Bogdanov ◽  
Hongyu Wu ◽  
Anren Song ◽  
...  
Keyword(s):  
Sphingosine Kinase ◽  
Sphingosine Kinase 1 ◽  
Adenosine A2b Receptor ◽  
Sickle Erythrocyte ◽  
Key Points ◽  
A2b Receptor ◽  
Specific Antagonist ◽  
Adenosine A2b ◽  
Adenosine Signaling

Key Points Adenosine signaling via ADORA2B induces SphK1 activity in sickle and normal erythrocytes via PKA-mediated ERK1/2 activation. Lowering adenosine by PEG-ADA or interfering ADORA2B activation by specific antagonist decreases SphK1 activity in normal and sickle RBCs.

Novel Adenosine A2B Receptor Signalling in Cardiac Fibroblasts: Uncovering Context-Specific Biased Agonism

2018 ◽  
Vol 27 ◽  
pp. S115-S116
Author(s):  
E. Vecchio ◽  
J. Baltos ◽  
C. Qin ◽  
R. Ritchie ◽  
A. Christopoulos ◽  
...  
Keyword(s):  
Cardiac Fibroblasts ◽  
Adenosine A2b Receptor ◽  
Biased Agonism ◽  
Receptor Signalling ◽  
A2b Receptor ◽  
Context Specific ◽  
Adenosine A2b
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