Mirogabalin, a novel ligand for α2δ subunit of voltage-gated calcium channels, improves cognitive impairments in repeated intramuscular acidic saline injection model rats, an experimental model of fibromyalgia

Injection Model ◽

Analgesic effects of mirogabalin, a novel ligand for α2δ subunit of voltage-gated calcium channels, in experimental animal models of fibromyalgia

Naunyn-Schmiedeberg s Archives of Pharmacology ◽

10.1007/s00210-019-01628-z ◽

2019 ◽

Vol 392 (6) ◽

pp. 723-728 ◽

Cited By ~ 5

Author(s):

Kensuke Saeki ◽

Shun-ichi Yasuda ◽

Masami Kato ◽

Mayumi Kano ◽

Yuki Domon ◽

...

Keyword(s):

Animal Models ◽

Calcium Channels ◽

Experimental Animal ◽

Experimental Animal Models ◽

Voltage Gated ◽

Analgesic Effects ◽

N-Acridin-9-yl-butane-1,4-diamine Derivatives: High Affinity Ligands of the α2δ Subunit of Voltage Gated Calcium Channels.

ChemInform ◽

10.1002/chin.200431123 ◽

2004 ◽

Vol 35 (31) ◽

Author(s):

Jongwon Lim ◽

et al. et al.

Keyword(s):

Calcium Channels ◽

Affinity Ligands ◽

Voltage Gated ◽

High Affinity ◽

N-Acridin-9-yl-butane-1,4-diamine derivatives: high-affinity ligands of the α2δ subunit of voltage gated calcium channels

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2004.01.087 ◽

2004 ◽

Vol 14 (8) ◽

pp. 1913-1916 ◽

Cited By ~ 9

Author(s):

Jongwon Lim ◽

Nicholas Stock ◽

Richard Pracitto ◽

Julia K Boueres ◽

Benito Munoz ◽

...

Keyword(s):

Calcium Channels ◽

Affinity Ligands ◽

Voltage Gated ◽

High Affinity ◽

Synthesis and Biological Evaluation of 6-Aryl-6H-pyrrolo[3,4-d]pyridazine Derivatives as High-Affinity Ligands of the α2δ Subunit of Voltage-Gated Calcium Channels.

ChemInform ◽

10.1002/chin.200435132 ◽

2004 ◽

Vol 35 (35) ◽

Author(s):

Tao Hu ◽

et al. et al.

Keyword(s):

Calcium Channels ◽

Biological Evaluation ◽

Affinity Ligands ◽

Voltage Gated ◽

High Affinity ◽

Synthesis And Biological Evaluation

Α2δ Subunit ◽

Pyridazine Derivatives ◽

Synthesis and Biological Evaluation of 6-Aryl-6H-pyrrolo[3,4-d]pyridazine Derivatives: High-Affinity Ligands to the α2δ Subunit of Voltage Gated Calcium Channels.

ChemInform ◽

10.1002/chin.200426126 ◽

2004 ◽

Vol 35 (26) ◽

Author(s):

Brian A. Stearns ◽

et al. et al.

Keyword(s):

Calcium Channels ◽

Biological Evaluation ◽

Affinity Ligands ◽

Voltage Gated ◽

High Affinity ◽

Synthesis And Biological Evaluation

Α2δ Subunit ◽

Pyridazine Derivatives ◽

Anxiolytic-like effects of mirogabalin, a novel ligand for α2δ ligand of voltage-gated calcium channels, in rats repeatedly injected with acidic saline intramuscularly, as an experimental model of fibromyalgia

Pharmacological Reports ◽

10.1007/s43440-020-00103-4 ◽

2020 ◽

Vol 72 (3) ◽

pp. 571-579

Author(s):

Hiroyasu Murasawa ◽

Hiroyuki Kobayashi ◽

Shun-ichi Yasuda ◽

Kensuke Saeki ◽

Yuki Domon ◽

...

Keyword(s):

Calcium Channels ◽

Experimental Model ◽

Voltage Gated ◽

Voltage Gated Calcium Channels

Expedited SAR study of high-affinity ligands to the α2δ subunit of voltage-gated calcium channels: Generation of a focused library using a solution-phase Sn2Ar coupling methodology

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2005.08.117 ◽

2006 ◽

Vol 16 (3) ◽

pp. 746-749 ◽

Cited By ~ 9

Author(s):

Chixu Chen ◽

Brian Stearns ◽

Tao Hu ◽

Naomi Anker ◽

Angelina Santini ◽

...

Keyword(s):

Calcium Channels ◽

Solution Phase ◽

Affinity Ligands ◽

Voltage Gated ◽

High Affinity ◽

Α2δ Subunit ◽

Sar Study

Structure–activity relationships of α-amino acid ligands for the α2δ subunit of voltage-gated calcium channels

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2005.11.108 ◽

2006 ◽

Vol 16 (5) ◽

pp. 1138-1141 ◽

Cited By ~ 22

Author(s):

Kathleen H. Mortell ◽

David J. Anderson ◽

James J. Lynch ◽

Sherry L. Nelson ◽

Kathy Sarris ◽

...

Keyword(s):

Amino Acid ◽

Calcium Channels ◽

Voltage Gated ◽

Structure Activity Relationships ◽

Structure Activity ◽

Binding Characteristics and Analgesic Effects of Mirogabalin, a Novel Ligand for the α2δ Subunit of Voltage-Gated Calcium Channels

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.117.247551 ◽

2018 ◽

Vol 365 (3) ◽

pp. 573-582 ◽

Cited By ~ 25

Author(s):

Yuki Domon ◽

Naohisa Arakawa ◽

Tatsuya Inoue ◽

Fumihiko Matsuda ◽

Makoto Takahashi ◽

...

Keyword(s):

Calcium Channels ◽

Binding Characteristics ◽

Voltage Gated ◽

Analgesic Effects ◽

Faculty Opinions recommendation of Voltage-gated calcium channels direct neuronal migration in Caenorhabditis elegans.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1001612.17075 ◽

2001 ◽

Author(s):

Oliver Hobert

Keyword(s):

Caenorhabditis Elegans ◽

Calcium Channels ◽

Neuronal Migration ◽

Voltage Gated ◽

Voltage Gated Calcium Channels