Efficient single whole-cell biotransformation for L-2-aminobutyric acid production through engineering of leucine dehydrogenase combined with expression regulation

2021 ◽  
pp. 124665
Author(s):  
Jiajie Chen ◽  
Rongshuai Zhu ◽  
Junping Zhou ◽  
Taowei Yang ◽  
Xian Zhang ◽  
...  
Keyword(s):  
Acid Production ◽  
Expression Regulation ◽  
Aminobutyric Acid ◽  
Whole Cell ◽  
Leucine Dehydrogenase ◽  
Whole Cell Biotransformation

Semi-Rational Engineering of Leucine Dehydrogenase for L-2-Aminobutyric Acid Production

2016 ◽  
Vol 182 (3) ◽  
pp. 898-909 ◽  
Author(s):  
Jian-Miao Xu ◽  
Feng Cheng ◽  
Fang-Tian Fu ◽  
Hai-Feng Hu ◽  
Yu-Guo Zheng
Keyword(s):  
Acid Production ◽  
Aminobutyric Acid ◽  
Rational Engineering ◽  
Leucine Dehydrogenase

Asymmetric reduction of a key intermediate of eslicarbazepine acetate using whole cell biotransformation in a biphasic medium

2012 ◽  
Vol 2 (8) ◽  
pp. 1602 ◽  
Author(s):  
Manpreet Singh ◽  
Sawraj Singh ◽  
Sateesh Deshaboina ◽  
Hare Krishnen ◽  
Richard Lloyd ◽  
...  
Keyword(s):  
Asymmetric Reduction ◽  
Eslicarbazepine Acetate ◽  
Whole Cell ◽  
Whole Cell Biotransformation ◽  
Biphasic Medium

Glyoxylate Carboligase-based Whole-Cell Biotransformation of Formaldehyde into Ethylene Glycol via Glycolaldehyde

2021 ◽  
Author(s):  
Hye-Jin Jo ◽  
Jun-Hong Kim ◽  
Ye-Na Kim ◽  
Pil-Won Seo ◽  
Chae-Yun Kim ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Whole Cell ◽  
Whole Cell Biotransformation

A novel biocatalytic system for the synthesis of the industrially relevant C2 chemicals (e.g., ethylene glycol (3)) from formaldehyde (1) was established. The biocatalytic system consisted of a newly discovered...

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