An unexpected full neurological recovery after cardiac arrest in a sickle cell anemia patient with bilateral cervical carotid artery disease

Abstract We have determined the nucleotide sequence of the 2,360-bp long EcoRI fragment from four chromosomes; this fragment is located 3′ to the A gamma globin gene and is considered to contain the enhancer element identified by Bodine and Ley. The chromosomes were from an Arabian sickle cell anemia patient with high Hb F and a homozygosity for haplotype No 31 and from a black sickle cell anemia patient with low Hb F and a homozygosity for haplotype No 19. A third chromosome carried the determinant for a nondeletional hereditary persistence of fetal hemoglobin seen in a Chinese subject, and the fourth was a normal chromosome from a Yugoslavian subject. Twenty-one differences were observed when a comparison was made with the published sequence; no differences were seen between the sequences of the four different samples except for an additional mutation in the Chinese. These data make it unlikely that specific mutations within this sequence are associated with increases in G gamma and A gamma production.

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Mycobacterium avium Complex-Associated Hemophagocytic Lymphohistiocytosis in a Sickle Cell Patient: An Unusual Fatal Association

Case Reports in Hematology ◽

10.1155/2013/291518 ◽

2013 ◽

Vol 2013 ◽

pp. 1-3 ◽

Cited By ~ 4

Author(s):

Mohammed A. R. Chamsi-Pasha ◽

M. Chadi Alraies ◽

Abdul Hamid Alraiyes ◽

Eric D. Hsi

Keyword(s):

Sickle Cell ◽

Mycobacterium Avium ◽

Sickle Cell Anemia ◽

Hemophagocytic Lymphohistiocytosis ◽

Mycobacterium Avium Complex ◽

Sickle Cell Anemia Patient ◽

Anemia Patient

Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome, characterized clinically by fever, splenomegaly, cytopenia, and high ferritin. Infectious causes have been associated with secondary HLH, with viruses being the most common. We report a case ofMycobacterium avium complex-associated HLH in a sickle cell anemia patient. To the best of our knowledge, this association has never been reported in sickle cell anemia.

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Uncommon sites of bone infarction in a sickle cell anemia patient

European Journal of Nuclear Medicine ◽

10.1007/bf00253549 ◽

1983 ◽

Vol 8 (8) ◽

Cited By ~ 8

Author(s):

I. Garty ◽

A. Koren ◽

E. Katzumi

Keyword(s):

Sickle Cell ◽

Sickle Cell Anemia ◽

Sickle Cell Anemia Patient ◽

Bone Infarction ◽

Anemia Patient

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569 Thoracoscopic Sympathectomy for Long-Qt Syndrome In a Sickle Cell Anemia Patient

Archives of Disease in Childhood ◽

10.1136/archdischild-2012-302724.0569 ◽

2012 ◽

Vol 97 (Suppl 2) ◽

pp. A165-A165

Author(s):

B. Banieghbal ◽

J. Harrisberg

Keyword(s):

Sickle Cell ◽

Sickle Cell Anemia ◽

Long Qt Syndrome ◽

Long Qt ◽

Thoracoscopic Sympathectomy ◽

Sickle Cell Anemia Patient ◽

Qt Syndrome ◽

Anemia Patient

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Identical nucleotide sequences of the 3'A gamma globin gene enhancer elements from four different chromosomes

Blood ◽

10.1182/blood.v73.3.845.bloodjournal733845 ◽

1989 ◽

Vol 73 (3) ◽

pp. 845-848

Author(s):

IS Han ◽

HJ Huang ◽

YT Zeng ◽

KD Lanclos ◽

TH Huisman

Keyword(s):

Sickle Cell ◽

Sickle Cell Anemia ◽

Globin Gene ◽

Fetal Hemoglobin ◽

Enhancer Element ◽

Gamma Globin ◽

Sickle Cell Anemia Patient ◽

Gene Enhancer ◽

Identical Nucleotide ◽

Anemia Patient

We have determined the nucleotide sequence of the 2,360-bp long EcoRI fragment from four chromosomes; this fragment is located 3′ to the A gamma globin gene and is considered to contain the enhancer element identified by Bodine and Ley. The chromosomes were from an Arabian sickle cell anemia patient with high Hb F and a homozygosity for haplotype No 31 and from a black sickle cell anemia patient with low Hb F and a homozygosity for haplotype No 19. A third chromosome carried the determinant for a nondeletional hereditary persistence of fetal hemoglobin seen in a Chinese subject, and the fourth was a normal chromosome from a Yugoslavian subject. Twenty-one differences were observed when a comparison was made with the published sequence; no differences were seen between the sequences of the four different samples except for an additional mutation in the Chinese. These data make it unlikely that specific mutations within this sequence are associated with increases in G gamma and A gamma production.

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