Computer-aided design and three-dimensional printing improves symmetry in heminasal reconstruction outcomes

2019 ◽  
Vol 72 (7) ◽  
pp. 1198-1206 ◽  
Author(s):  
Cheng-I Yen ◽  
Jonathan A. Zelken ◽  
Chun-Shin Chang ◽  
Lun-Jou Lo ◽  
Jui-Yung Yang ◽  
...  
Keyword(s):  
Computer Aided Design ◽  
Three Dimensional ◽  
Three Dimensional Printing ◽  
Computer Aided ◽  
Aided Design ◽  
Dimensional Printing

Computer-aided design and three-dimensional printing in the manufacturing of an ocular prosthesis

2016 ◽  
Vol 100 (7) ◽  
pp. 879-881 ◽  
Author(s):  
Sébastien Ruiters ◽  
Yi Sun ◽  
Stéphan de Jong ◽  
Constantinus Politis ◽  
Ilse Mombaerts
Keyword(s):  
Computer Aided Design ◽  
Three Dimensional ◽  
Three Dimensional Printing ◽  
Ocular Prosthesis ◽  
Computer Aided ◽  
Aided Design ◽  
Dimensional Printing

scholarly journals Three-dimensional printing of a patient-specific engineered nasal cartilage for augmentative rhinoplasty

2019 ◽  
Vol 10 ◽  
pp. 204173141882479 ◽  
Author(s):  
Hee-Gyeong Yi ◽  
Yeong-Jin Choi ◽  
Jin Woo Jung ◽  
Jinah Jang ◽  
Tae-Ha Song ◽  
...  
Keyword(s):  
Stem Cells ◽  
Computer Aided Design ◽  
Three Dimensional ◽  
Patient Specific ◽  
Adipose Derived Stem Cells ◽  
Three Dimensional Printing ◽  
Nasal Cartilage ◽  
Computer Aided ◽  
Aided Design ◽  
Dimensional Printing

Autologous cartilages or synthetic nasal implants have been utilized in augmentative rhinoplasty to reconstruct the nasal shape for therapeutic and cosmetic purposes. Autologous cartilage is considered to be an ideal graft, but has drawbacks, such as limited cartilage source, requirements of additional surgery for obtaining autologous cartilage, and donor site morbidity. In contrast, synthetic nasal implants are abundantly available but have low biocompatibility than the autologous cartilages. Moreover, the currently used nasal cartilage grafts involve additional reshaping processes, by meticulous manual carving during surgery to fit the diverse nose shape of each patient. The final shapes of the manually tailored implants are highly dependent on the surgeons’ proficiency and often result in patient dissatisfaction and even undesired separation of the implant. This study describes a new process of rhinoplasty, which integrates three-dimensional printing and tissue engineering approaches. We established a serial procedure based on computer-aided design to generate a three-dimensional model of customized nasal implant, and the model was fabricated through three-dimensional printing. An engineered nasal cartilage implant was generated by injecting cartilage-derived hydrogel containing human adipose-derived stem cells into the implant containing the octahedral interior architecture. We observed remarkable expression levels of chondrogenic markers from the human adipose-derived stem cells grown in the engineered nasal cartilage with the cartilage-derived hydrogel. In addition, the engineered nasal cartilage, which was implanted into mouse subcutaneous region, exhibited maintenance of the exquisite shape and structure, and striking formation of the cartilaginous tissues for 12 weeks. We expect that the developed process, which combines computer-aided design, three-dimensional printing, and tissue-derived hydrogel, would be beneficial in generating implants of other types of tissue.

scholarly journals Utilising three-dimensional printing techniques when providing unique assistive devices: A case report

2017 ◽  
Vol 42 (1) ◽  
pp. 45-49 ◽  
Author(s):  
Sarah Jane Day ◽  
Shaun Patrick Riley
Keyword(s):  
Patient Satisfaction ◽  
Computer Aided Design ◽  
Three Dimensional ◽  
Assistive Device ◽  
Additive Manufacture ◽  
Three Dimensional Printing ◽  
Computer Aided ◽  
Aided Design ◽  
Dimensional Printing ◽  
Printing Techniques

Background: The evolution of three-dimensional printing into prosthetics has opened conversations about the availability and cost of prostheses. This report will discuss how a prosthetic team incorporated additive manufacture techniques into the treatment of a patient with a partial hand amputation to create and test a unique assistive device which he could use to hold his French horn. Case description and methods: Using a process of shape capture, photogrammetry, computer-aided design and finite element analysis, a suitable assistive device was designed and tested. The design was fabricated using three-dimensional printing. Patient satisfaction was measured using a Pugh’s Matrix™, and a cost comparison was made between the process used and traditional manufacturing. Findings and outcomes: Patient satisfaction was high. The three-dimensional printed devices were 56% cheaper to fabricate than a similar laminated device. Conclusion: Computer-aided design and three-dimensional printing proved to be an effective method for designing, testing and fabricating a unique assistive device. Clinical relevance CAD and 3D printing techniques can enable devices to be designed, tested and fabricated cheaper than when using traditional techniques. This may lead to improvements in quality and accessibility.

scholarly journals Feature Focus: Rapid Prototyping: Rapid Evolution

2002 ◽  
Vol 124 (03) ◽  
pp. 48-52
Author(s):  
John DeGaspari
Keyword(s):  
Injection Molding ◽  
Rapid Prototyping ◽  
Computer Aided Design ◽  
Rapid Evolution ◽  
Three Dimensional ◽  
Three Dimensional Printing ◽  
Computer Aided ◽  
Physical Objects ◽  
Aided Design ◽  
Dimensional Printing

This article highlights the striking facts about rapid prototyping; a process that fabricates physical objects directly from computer-aided design sources. The use of rapid prototyping as a replacement for injection molding is still the overwhelming exception and may always be limited to a very narrow niche. Three-dimensional printing has also seen the introduction of materials that improve the durability and appearance of conceptual prototype parts. Z Corp. of Burlington is incorporating new pigments into its binders for its starch- and plaster-based materials. The pigments result in truer and brighter colors and replace the dyes that were previously incorporated into the liquid binders. The company has recently introduced a urethane infiltrant that increases part strength significantly and allows parts with delicate geometries to be.

scholarly journals 3D Printing Technology in Pharmaceutical Drug Delivery

2021 ◽  
Vol 68 (1) ◽  
Keyword(s):  
Drug Delivery ◽  
3D Printing ◽  
Computer Aided Design ◽  
Three Dimensional ◽  
Pharmaceutical Manufacturing ◽  
Three Dimensional Printing ◽  
Pharmaceutical Drug ◽  
Pharmaceutical Technology ◽  
Aided Design ◽  
Dimensional Printing

Three dimensional printing (3DP) enables the development of diverse geometries through computer aided design using different techniques and materials for desired applications such as pharmaceutical drug delivery system. The process of 3D printing was patented in 1986; however, the research in the field of 3DP did not become popular until the last decade. There has been an increasing research into the areas of 3DP for medical applications for fabricating prosthetics, bioprinting and pharmaceutics. It becomes one of the most innovatory and influential tools serving as a technology of precise manufacturing of developed dosage forms, tissue engineering and disease modelling. It is a valuable strategy to overcome some challenges of conventional pharmaceutical process. This technology will reform the pharmaceutical manufacturing style and formulation techniques. The present review focused on various techniques, applications of 3D printing in pharmaceutical technology.

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