Microfluidic Pressure in Paper (µPiP): Rapid Prototyping and Low-Cost Liquid Handling for On-Chip Diagnostics

Paper-based microfluidics was initially developed for use in ultra-low-cost diagnostics powered passively by liquid wicking. However, there is significant untapped potential in using paper to internally guide porous microfluidic flows...

An ICT Prototyping Framework for the “Port of the Future”

Seaports are genuine, intermodal hubs connecting seaways to inland transport links, such as roads and railways. Seaports are located at the focal point of institutional, industrial, and control activities in a jungle of interconnected information systems. System integration is setting considerable challenges when a group of independent providers are asked to implement complementary software functionalities. For this reason, seaports are the ideal playground where software is highly composite and tailored to a large variety of final users (from the so-called port communities). Although the target would be that of shaping the Port Authorities to be providers of (digital) innovation services, the state-of-the-art is still that of considering them as final users, or proxies of them. For this reason, we show how a canonical cloud, virtualizing a distributed architecture, can be structured to host different, possibly overlapped, tenants, slicing the information system at the infrastructure, platform, and software layers. Resources at the infrastructure and platform layers are shared so that a variety of independent applications can make use of the local calculus and access the data stored in a Data Lake. Such a cloud is adopted by the Port of Livorno as a rapid prototyping framework for the development and deployment of ICT innovation services. In order to demonstrate the versatility of this framework, three case studies relating to as many prototype ICT services (Navigation Safety, e-Freight, and Logistics) released within three industrial tenants are here presented and discussed.

Method for Segmentation and Hybrid Joining of Additive Manufactured Segments in Prototyping Using the Example of Trim Parts

Rapid prototyping has become increasingly popular over the past years. However, its application is heavily confined to a part size that fits the small build volume of additive machines. This paper presents a universal design method to overcome this limitation while preserving the economic advantages of rapid prototyping over conventional processes. It segments large, thin-walled parts and joins the segments. The method aims to produce an assembly with minimal loss to the performance and characteristics of a solid part. Based on a set of requirements, a universal segmentation approach and a novel hybrid joint design combining adhesive bonding and press fitting are developed. This design allows for the force transmission, positioning, and assembly of the segments adaptive to their individual geometry. The method is tailored to fused deposition modeling (FDM) by minimizing the need for support structures and actively compensating for manufacturing tolerances. While a universal application cannot be guaranteed, the adaptive design was proven for a variety of complex geometries. Using automotive trim parts as an example, the usability, benefits, and novelty of the design method is presented. The method itself shows a high potential to overcome the build volume limitation for thin-walled parts in an economic manner.

Rapid Prototyping of Organ-on-a-Chip Devices Using Maskless Photolithography

Organ-on-a-chip (OoC) and microfluidic devices are conventionally produced using microfabrication procedures that require cleanrooms, silicon wafers, and photomasks. The prototyping stage often requires multiple iterations of design steps. A simplified prototyping process could therefore offer major advantages. Here, we describe a rapid and cleanroom-free microfabrication method using maskless photolithography. The approach utilizes a commercial digital micromirror device (DMD)-based setup using 375 nm UV light for backside exposure of an epoxy-based negative photoresist (SU-8) on glass coverslips. We show that microstructures of various geometries and dimensions, microgrooves, and microchannels of different heights can be fabricated. New SU-8 molds and soft lithography-based polydimethylsiloxane (PDMS) chips can thus be produced within hours. We further show that backside UV exposure and grayscale photolithography allow structures of different heights or structures with height gradients to be developed using a single-step fabrication process. Using this approach: (1) digital photomasks can be designed, projected, and quickly adjusted if needed; and (2) SU-8 molds can be fabricated without cleanroom availability, which in turn (3) reduces microfabrication time and costs and (4) expedites prototyping of new OoC devices.

POSSIBILITIES OF INDUSTRIAL UTILIZATION OF FFF/FDM PROCESS FOR CHOSEN ELEMENT PRINTing

3D printing is a one of a new solution of manufacturing methods. This is caused by the ability of print a small part in a short time (rapid prototyping), but also because of the available materials. This is important because by using 3D printing, a specialized element is made for a specific apply. Compared with traditional production methods, such as turning and milling, 3D printing gives a wider possibility of making specific product patterns, thanks to which this method gained support and became a competitive one. Hence, the designing and manufacturing process based on it is more and more often referred as the “design-driven manufacturing”. This method gives the possibility of making personalized elements or a larger number of product variants, but also gives the possibility of manufacturing complete elements in one run. The article describes the possibilities of using 3D printing in the production of unusual elements in a uncertain situations.