scholarly journals Unexplained hemorrhagic syndrome? Consider acquired hemophilia A or B

Blood Reviews ◽  
2021 ◽  
pp. 100907
Author(s):  
Catalin Constantinescu ◽  
Ciprian Jitaru ◽  
Sergiu Pasca ◽  
Delia Dima ◽  
Noemi Dirzu ◽  
...  
2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Quentin Binet ◽  
Catherine Lambert ◽  
Laurine Sacré ◽  
Stéphane Eeckhoudt ◽  
Cedric Hermans

Background. Acquired hemophilia A (AHA) is a rare condition, due to the spontaneous formation of neutralizing antibodies against endogenous factor VIII. About half the cases are associated with pregnancy, postpartum, autoimmune diseases, malignancies, or adverse drug reactions. Symptoms include severe and unexpected bleeding that may prove life-threatening.Case Study. We report a case of AHA associated with bullous pemphigoid (BP), a chronic, autoimmune, subepidermal, blistering skin disease. To our knowledge, this is the 25th documented case of such an association. Following treatment for less than 3 months consisting of methylprednisolone at decreasing dose levels along with four courses of rituximab (monoclonal antibody directed against the CD20 protein), AHA was completely cured and BP well-controlled.Conclusions. This report illustrates a rare association of AHA and BP, supporting the possibility of eradicating the inhibitor with a well-conducted short-term treatment.


2013 ◽  
Vol 46 (4) ◽  
pp. 135-139
Author(s):  
Chia-Wei Chang ◽  
Jiun-Ting Yeh ◽  
Shang-Yu Wang ◽  
Chun-Hsiang Ouyang ◽  
Chien-Hung Liao ◽  
...  

2005 ◽  
Vol 40 (1) ◽  
pp. 58 ◽  
Author(s):  
Sun Young Park ◽  
Jin Seok Kim ◽  
Yuri Kim ◽  
In Hae Park ◽  
June-Won Cheong ◽  
...  

2011 ◽  
Vol 26 (9) ◽  
pp. 1247 ◽  
Author(s):  
Ji Hyun Lee ◽  
Dong-Hwan Kim ◽  
Kiyoung Yoo ◽  
Yongmook Choi ◽  
Sun-Hee Kim ◽  
...  

2013 ◽  
Vol 59 (12) ◽  
pp. 786-790
Author(s):  
Katsumi MOTEGI ◽  
Yukihiro MOMOTA ◽  
Hideyuki TAKANO ◽  
Kouichi KANI ◽  
Yoshiko YAMAMURA ◽  
...  

Blood ◽  
2021 ◽  
Vol 137 (3) ◽  
pp. 294-295
Author(s):  
Sergio Siragusa ◽  
Mariasanta Napolitano

2012 ◽  
Vol 73 (8) ◽  
pp. 2002-2006
Author(s):  
Tatsuo MATSUDA ◽  
Sumire OTANI ◽  
Jieefun RIYUU ◽  
Shigeo HAYATSU ◽  
Hiroto ISHIZUKA ◽  
...  

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