Design, synthesis and biological evaluation of anthranilamide derivatives as potential factor Xa (fXa) inhibitors

Identification of anthranilamide derivatives as potential factor Xa inhibitors: Drug design, synthesis and biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2015.03.052 ◽

2015 ◽

Vol 95 ◽

pp. 388-399 ◽

Cited By ~ 15

Author(s):

Junhao Xing ◽

Lingyun Yang ◽

Hui Li ◽

Qing Li ◽

Leilei Zhao ◽

...

Keyword(s):

Drug Design ◽

Factor Xa ◽

Biological Evaluation ◽

Factor Xa Inhibitors ◽

Design Synthesis ◽

Potential Factor ◽

Design, Synthesis, and Biological Evaluation of Potent and Selective Amidino Bicyclic Factor Xa Inhibitors

Journal of Medicinal Chemistry ◽

10.1021/jm000113t ◽

2000 ◽

Vol 43 (23) ◽

pp. 4398-4415 ◽

Cited By ~ 34

Author(s):

Qi Han ◽

Celia Dominguez ◽

Pieter F. W. Stouten ◽

Jeongsook M. Park ◽

Daniel E. Duffy ◽

...

Keyword(s):

Factor Xa ◽

Biological Evaluation ◽

Factor Xa Inhibitors ◽

Design Synthesis ◽

Prodrug-based design, synthesis, and biological evaluation of N-benzenesulfonylpiperidine derivatives as novel, orally active factor Xa inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2007.03.066 ◽

2007 ◽

Vol 15 (12) ◽

pp. 4175-4192 ◽

Cited By ~ 9

Author(s):

Tsukasa Ishihara ◽

Norio Seki ◽

Fukushi Hirayama ◽

Masaya Orita ◽

Hiroyuki Koshio ◽

...

Keyword(s):

Factor Xa ◽

Biological Evaluation ◽

Factor Xa Inhibitors ◽

Design Synthesis ◽

Active Factor ◽

Orally Active ◽

Design, Synthesis and Biological Evaluation of some Chalcone Derivatives as Potential Pancreatic Lipase Inhibitors

10.3390/ecsoc-17-b024 ◽

2013 ◽

Author(s):

Dao Tran

Keyword(s):

Pancreatic Lipase ◽

Biological Evaluation ◽

Design Synthesis ◽

Chalcone Derivatives ◽

Pancreatic Lipase Inhibitors ◽

Faculty Opinions recommendation of Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726271231.793520213 ◽

2016 ◽

Author(s):

Miles Congreve ◽

Mark Pickworth

Keyword(s):

G Protein ◽

Biological Evaluation ◽

Receptor Kinase ◽

G Protein Coupled Receptor ◽

Design Synthesis ◽

G Protein Coupled ◽

Design, Synthesis and Biological Evaluation of Hybrid Molecules Containing Conjugated Styryl Ketone and α-Bromoacryloyl Moieties

10.2174/157018012799079842 ◽

2012 ◽

Vol 9 (2) ◽

pp. 140-152 ◽

Cited By ~ 1

Author(s):

Romeo Romagnoli ◽

Pier Giovanni Baraldi ◽

Olga Cruz-Lopez ◽

Maria Kimatrai Salvador ◽

Delia Preti ◽

...

Keyword(s):

Biological Evaluation ◽

Design Synthesis ◽

Hybrid Molecules ◽

Design, Synthesis and Biological Evaluation of Novel Aminosaccharide Derivatives of Combretastatin A-4

10.2174/15701808113109990024 ◽

2013 ◽

Vol 10 (10) ◽

pp. 935-941

Author(s):

Yan Tang ◽

Zhewei Tu ◽

Jing Sun ◽

Xiong Zhu ◽

Kun Liu ◽

...

Keyword(s):

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Derivatives Of

Design, Synthesis and Biological Evaluation of Some Oxadiazole Derivatives as Novel Amide-Based Inhibitors of Soluble Epoxide Hydrolase

10.2174/1570180811666140220005530 ◽

2014 ◽

Vol 11 (6) ◽

pp. 721-730 ◽

Cited By ~ 8

Author(s):

Elham Zavareh ◽

Mahdi Hedayati ◽

Laleh Rad ◽

Azin Kiani ◽

Soraya Shahhosseini ◽

...

Keyword(s):

Epoxide Hydrolase ◽

Soluble Epoxide Hydrolase ◽

Biological Evaluation ◽

Design Synthesis ◽

Oxadiazole Derivatives ◽

Rational Design, Synthesis and Biological Evaluation of Novel Derivatives Based on in vivo Metabolism of Natural Product β-elemene

10.2174/1570180814666171108093021 ◽

2018 ◽

Vol 15 (8) ◽

pp. 905-912 ◽

Cited By ~ 1

Author(s):

Renren Bai ◽

Xiaokang Jie ◽

Eric Salgado ◽

Jian Sun ◽

Yao Zhu ◽

...

Keyword(s):

Natural Product ◽

Rational Design ◽

Biological Evaluation ◽

In Vivo Metabolism ◽

Design Synthesis ◽

Design, Synthesis and Biological Evaluation of Benzopyran Derivatives as KATP Channel Openers

10.2174/157018010791306560 ◽

2010 ◽

Vol 7 (6) ◽

pp. 415-420 ◽

Cited By ~ 3

Author(s):

Jinpei Zhou ◽

Hai Qian ◽

Huibin Zhang ◽

Hui Gao ◽

Wenlong Huang ◽

...

Keyword(s):

Katp Channel ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Katp Channel Openers