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Novel Hybrid Conjugates with Dual Estrogen Receptor α Degradation and Histone Deacetylase Inhibitory Activities for Breast Cancer Therapy
Bioorganic & Medicinal Chemistry
◽
10.1016/j.bmc.2021.116185
◽
2021
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pp. 116185
Author(s):
Chenxi Zhao
◽
Chu Tang
◽
Changhao Li
◽
Wentao Ning
◽
Zhiye Hu
◽
...
Keyword(s):
Breast Cancer
◽
Estrogen Receptor
◽
Cancer Therapy
◽
Histone Deacetylase
◽
Estrogen Receptor Α
◽
Breast Cancer Therapy
◽
Inhibitory Activities
Download Full-text
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References
Abstract P3-05-04: Estrogen receptor α-regulation of nucleocytoplasmic transport pathways as modulators of breast cancer therapy effectiveness
10.1158/1538-7445.sabcs15-p3-05-04
◽
2016
◽
Author(s):
Z Madak-Erdogan
◽
Y Chen-Zhao
◽
K Wrobel
Keyword(s):
Breast Cancer
◽
Estrogen Receptor
◽
Cancer Therapy
◽
Nucleocytoplasmic Transport
◽
Estrogen Receptor Α
◽
Breast Cancer Therapy
◽
Transport Pathways
◽
Therapy Effectiveness
Download Full-text
Estrogen receptor agonists/antagonists in breast cancer therapy: A critical review
Bioorganic Chemistry
◽
10.1016/j.bioorg.2017.02.011
◽
2017
◽
Vol 71
◽
pp. 257-274
◽
Cited By ~ 62
Author(s):
A. Jameera Begam
◽
S. Jubie
◽
M.J. Nanjan
Keyword(s):
Breast Cancer
◽
Estrogen Receptor
◽
Cancer Therapy
◽
Critical Review
◽
Breast Cancer Therapy
◽
Receptor Agonists
Download Full-text
Advances in estrogen receptor biology: prospects for improvements in targeted breast cancer therapy
Breast Cancer Research
◽
10.1186/bcr742
◽
2003
◽
Vol 6
(1)
◽
Cited By ~ 113
Author(s):
Wenlin Shao
◽
Myles Brown
Keyword(s):
Breast Cancer
◽
Estrogen Receptor
◽
Cancer Therapy
◽
Breast Cancer Therapy
◽
Receptor Biology
Download Full-text
The role of selective estrogen receptor destabilizers (SERDs) in breast cancer therapy
Drugs of the Future
◽
10.1358/dof.2016.041.06.2482681
◽
2016
◽
Vol 41
(6)
◽
pp. 361
Author(s):
R.V. Weatherman
Keyword(s):
Breast Cancer
◽
Estrogen Receptor
◽
Cancer Therapy
◽
Breast Cancer Therapy
Download Full-text
Can estrogen receptor overexpression in normal tissues due to previous estrogen deprivation explain the fulvestrant efficacy in breast cancer therapy?
Medical Hypotheses
◽
10.1016/j.mehy.2012.09.010
◽
2012
◽
Vol 79
(6)
◽
pp. 869-871
◽
Cited By ~ 1
Author(s):
Sven Kurbel
Keyword(s):
Breast Cancer
◽
Estrogen Receptor
◽
Cancer Therapy
◽
Estrogen Deprivation
◽
Breast Cancer Therapy
◽
Normal Tissues
Download Full-text
Enhanced noscapine delivery using estrogen-receptor-targeted nanoparticles for breast cancer therapy
Anti-Cancer Drugs
◽
10.1097/cad.0000000000000098
◽
2014
◽
pp. 1
Author(s):
Jitender Madan
◽
Sushma R. Gundala
◽
Yoganjaneyulu Kasetti
◽
Prasad V. Bharatam
◽
Ritu Aneja
◽
...
Keyword(s):
Breast Cancer
◽
Estrogen Receptor
◽
Cancer Therapy
◽
Breast Cancer Therapy
◽
Targeted Nanoparticles
Download Full-text
Cover Picture: A Chimeric SERM-Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy (ChemMedChem 3/2014)
ChemMedChem
◽
10.1002/cmdc.201490005
◽
2014
◽
Vol 9
(3)
◽
pp. 413-413
Author(s):
Hitisha K. Patel
◽
Marton I. Siklos
◽
Hazem Abdelkarim
◽
Emma L. Mendonca
◽
Aditya Vaidya
◽
...
Keyword(s):
Breast Cancer
◽
Cancer Therapy
◽
Histone Deacetylase
◽
Histone Deacetylase Inhibitor
◽
Breast Cancer Therapy
◽
Deacetylase Inhibitor
Download Full-text
Quercetin exerts bidirectional regulation effects on the efficacy of tamoxifen in estrogen receptor‐positive breast cancer therapy: An in vitro study
Environmental Toxicology
◽
10.1002/tox.22983
◽
2020
◽
Vol 35
(11)
◽
pp. 1179-1193
Author(s):
Zhixiang Xu
◽
Dimeng Zhao
◽
Xianyao Zheng
◽
Bin Huang
◽
Xueshan Xia
◽
...
Keyword(s):
Breast Cancer
◽
Estrogen Receptor
◽
Cancer Therapy
◽
In Vitro Study
◽
Vitro Study
◽
Breast Cancer Therapy
◽
Bidirectional Regulation
◽
Estrogen Receptor Positive
◽
Positive Breast Cancer
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A Novel Strategy to Co-target Estrogen Receptor and Nuclear Factor κB Pathways with Hybrid Drugs for Breast Cancer Therapy
Hormones and Cancer
◽
10.1007/s12672-017-0294-5
◽
2017
◽
Vol 8
(3)
◽
pp. 135-142
◽
Cited By ~ 3
Author(s):
Irida Kastrati
◽
Marton I. Siklos
◽
Svitlana D. Brovkovych
◽
Gregory R. J. Thatcher
◽
Jonna Frasor
Keyword(s):
Breast Cancer
◽
Estrogen Receptor
◽
Cancer Therapy
◽
Nuclear Factor Κb
◽
Nuclear Factor
◽
Breast Cancer Therapy
◽
Hybrid Drugs
◽
Novel Strategy
Download Full-text
The potential of histone deacetylase inhibitors in breast cancer therapy
Breast Cancer Management
◽
10.2217/bmt.14.56
◽
2015
◽
Vol 4
(2)
◽
pp. 85-97
◽
Cited By ~ 2
Author(s):
Namita Chatterjee
◽
Martin Tenniswood
Keyword(s):
Breast Cancer
◽
Cancer Therapy
◽
Histone Deacetylase
◽
Histone Deacetylase Inhibitors
◽
Breast Cancer Therapy
Download Full-text
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