Design, synthesis and biological evaluation of novel 2,4-disubstituted quinazoline derivatives targeting H1975 cells via EGFR-PI3K signaling pathway

2021 ◽  
Vol 43 ◽  
pp. 116265
Author(s):  
Zhengjie Wang ◽  
Limin Liu ◽  
Honglin Dai ◽  
Xiaojie Si ◽  
Luye Zhang ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Biological Evaluation ◽  
Pi3k Signaling ◽  
Design Synthesis ◽  
Pi3k Signaling Pathway ◽  
Quinazoline Derivatives ◽  
Synthesis And Biological Evaluation

scholarly journals Correction: Towards dual inhibitors of the MET kinase and WNT signaling pathway; design, synthesis and biological evaluation

RSC Advances ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 4927-4927
Author(s):  
Vegard Torp Lien ◽  
Margrethe Konstanse Kristiansen ◽  
Solveig Pettersen ◽  
Mads Haugland Haugen ◽  
Stefan Krauss ◽  
...  
Keyword(s):  
Wnt Signaling ◽  
Signaling Pathway ◽  
Wnt Signaling Pathway ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Dual Inhibitors ◽  
Synthesis And Biological Evaluation

Correction for ‘Towards dual inhibitors of the MET kinase and WNT signaling pathway; design, synthesis and biological evaluation’ by Vegard Torp Lien et al., RSC Adv., 2019, 9, 37092–37100.

scholarly journals Design, synthesis and biological evaluation of 2,3-dihydroimidazo[1,2-c]quinazoline derivatives as novel phosphatidylinositol 3-kinase and histone deacetylase dual inhibitors

RSC Advances ◽  
2017 ◽  
Vol 7 (82) ◽  
pp. 52180-52186 ◽  
Author(s):  
Yichao Wu ◽  
Weichen Dai ◽  
Xin Chen ◽  
Aixin Geng ◽  
Yadong Chen ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Inhibitory Activity ◽  
Biological Evaluation ◽  
Design Approach ◽  
Phosphatidylinositol 3 Kinase ◽  
Design Synthesis ◽  
Dual Inhibitors ◽  
Quinazoline Derivatives ◽  
Synthesis And Biological Evaluation ◽  
Novel Design

A novel design approach by combination of PI3K and HDAC inhibitory activity in one molecule to produce dual inhibitors.

Design, synthesis and biological evaluation of quinazoline derivatives as anti-trypanosomatid and anti-plasmodial agents

2015 ◽  
Vol 96 ◽  
pp. 296-307 ◽  
Author(s):  
César Mendoza-Martínez ◽  
José Correa-Basurto ◽  
Rocío Nieto-Meneses ◽  
Adrián Márquez-Navarro ◽  
Rocío Aguilar-Suárez ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Quinazoline Derivatives ◽  
Synthesis And Biological Evaluation

Design, synthesis, and biological evaluation of quinazoline derivatives as α-glucosidase inhibitors

2014 ◽  
Vol 24 (5) ◽  
pp. 2227-2237 ◽  
Author(s):  
Venkateshwarlu Gurram ◽  
Ramesh Garlapati ◽  
Chiranjeevi Thulluri ◽  
Nagaraju Madala ◽  
Kumara Swamy Kasani ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Glucosidase Inhibitors ◽  
Quinazoline Derivatives ◽  
Synthesis And Biological Evaluation
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