Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold

2008 ◽  
Vol 18 (5) ◽  
pp. 1623-1627 ◽  
Author(s):  
Mohane Selvaraj Coumar ◽  
Jian-Sung Wu ◽  
Jiun-Shyang Leou ◽  
Uan-Kang Tan ◽  
Chung-Yu Chang ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Aurora Kinase ◽  
Aurora Kinase A ◽  
Kinase A

Die Expression der Aurora Kinase A korreliert mit dem Wnt-Modulator RACGAP1 im Magenkarzinom

2015 ◽  
Vol 53 (08) ◽  
Author(s):  
J Bornschein ◽  
J Nielitz ◽  
I Drozdov ◽  
M Selgrad ◽  
T Wex ◽  
...  
Keyword(s):  
Aurora Kinase ◽  
Aurora Kinase A ◽  
Kinase A

scholarly journals Targeting Aurora kinase A and JAK2 prevents GVHD while maintaining Tregand antitumor CTL function

2017 ◽  
Vol 9 (372) ◽  
pp. eaai8269 ◽  
Author(s):  
Brian C. Betts ◽  
Anandharaman Veerapathran ◽  
Joseph Pidala ◽  
Hua Yang ◽  
Pedro Horna ◽  
...  
Keyword(s):  
Aurora Kinase ◽  
Aurora Kinase A ◽  
Kinase A

Inhibition of Aurora Kinase A enhances chemosensitivity of medulloblastoma cell lines

2010 ◽  
Vol 55 (1) ◽  
pp. 35-41 ◽  
Author(s):  
Ayman El-Sheikh ◽  
Rong Fan ◽  
Diane Birks ◽  
Andrew Donson ◽  
Nicholas K Foreman ◽  
...  
Keyword(s):  
Cell Lines ◽  
Aurora Kinase ◽  
Aurora Kinase A ◽  
Medulloblastoma Cell ◽  
Kinase A ◽  
Medulloblastoma Cell Lines

scholarly journals Aurora Kinase A Drives MTOC Biogenesis but Does Not Trigger Resumption of Meiosis in Mouse Oocytes Matured In Vivo1

2012 ◽  
Vol 87 (4) ◽  
Author(s):  
Petr Solc ◽  
Vladimir Baran ◽  
Alexandra Mayer ◽  
Tereza Bohmova ◽  
Gabriela Panenkova-Havlova ◽  
...  
Keyword(s):  
Aurora Kinase ◽  
Aurora Kinase A ◽  
Mouse Oocytes ◽  
Kinase A

1032 poster MLN8054, A NOVEL INHIBITOR OF AURORA KINASE A SENSITIZES ANDROGEN-RESISTANT PROSTATE CANCER MODELS TO RADIATION

2011 ◽  
Vol 99 ◽  
pp. S386
Author(s):  
L. Moretti ◽  
K. Niermann ◽  
S. Schleicher ◽  
K.W. Kim ◽  
P. Kopsombut ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Aurora Kinase ◽  
Aurora Kinase A ◽  
Cancer Models ◽  
Kinase A

scholarly journals How to design aurora kinase A selective inhibitors

2009 ◽  
Vol 65 (a1) ◽  
pp. s148-s149
Author(s):  
Magda Kosmopoulou ◽  
Amir Faisal ◽  
Chongbo Sun ◽  
Vassilios Bavetsias ◽  
Butrus Atrash ◽  
...  
Keyword(s):  
Aurora Kinase ◽  
Selective Inhibitors ◽  
Aurora Kinase A ◽  
Kinase A
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