Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of Type 2 diabetes: 2. Optimization of serine and threonine ether amino acid residues

2009 ◽  
Vol 19 (3) ◽  
pp. 981-985 ◽  
Author(s):  
Steven M. Sparks ◽  
Pierette Banker ◽  
David M. Bickett ◽  
Daphne C. Clancy ◽  
Scott H. Dickerson ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Amino Acid ◽  
Glycogen Phosphorylase ◽  
Amino Acid Residues ◽  
Glycogen Phosphorylase Inhibitors

Phytogenic Polyphenols as Glycogen Phosphorylase Inhibitors: The Potential of Triterpenes and Flavonoids for Glycaemic Control in Type 2 Diabetes

2017 ◽  
Vol 24 (4) ◽  
pp. 384-403 ◽  
Author(s):  
Demetres Leonidas ◽  
Joseph Hayes ◽  
Atsushi Kato ◽  
Vassiliki Skamnaki ◽  
Demetra Chatzileontiadou ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glycaemic Control ◽  
Glycogen Phosphorylase ◽  
Glycogen Phosphorylase Inhibitors

Acyl Ureas as Human Liver Glycogen Phosphorylase Inhibitors for the Treatment of Type 2 Diabetes

2005 ◽  
Vol 48 (20) ◽  
pp. 6178-6193 ◽  
Author(s):  
Thomas Klabunde ◽  
K. Ulrich Wendt ◽  
Dieter Kadereit ◽  
Volker Brachvogel ◽  
Hans-Jörg Burger ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Human Liver ◽  
Glycogen Phosphorylase ◽  
Liver Glycogen ◽  
Glycogen Phosphorylase Inhibitors

Pentacyclic triterpenes, inhibitors of glycogen phosphorylase, as potential drugs for type 2 diabetes: X-ray crystallographic studies

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
SE Zographos ◽  
DD Leonidas ◽  
KM Alexacou ◽  
T Gimisis ◽  
JM Hayes ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glycogen Phosphorylase ◽  
X Ray ◽  
Pentacyclic Triterpenes

301-LB: Effects of Amino Acid Restriction on Development of Type 2 Diabetes in NZO Mice by FGF21 Secretion

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 301-LB
Author(s):  
TERESA CASTAÑO-MARTINEZ ◽  
WENKE JONAS ◽  
DANIELA WEBER ◽  
CORNELIA WEIKERT ◽  
THOMAS LAEGER
Keyword(s):  
Type 2 Diabetes ◽  
Amino Acid ◽  
Nzo Mice
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