Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes: 1. Identification of 1-amino-1-cycloalkyl carboxylic acid headgroups

2009 ◽  
Vol 19 (3) ◽  
pp. 976-980 ◽  
Author(s):  
Steven M. Sparks ◽  
Pierette Banker ◽  
David M. Bickett ◽  
H. Luke Carter ◽  
Daphne C. Clancy ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Carboxylic Acid ◽  
Glycogen Phosphorylase ◽  
Glycogen Phosphorylase Inhibitors

Phytogenic Polyphenols as Glycogen Phosphorylase Inhibitors: The Potential of Triterpenes and Flavonoids for Glycaemic Control in Type 2 Diabetes

2017 ◽  
Vol 24 (4) ◽  
pp. 384-403 ◽  
Author(s):  
Demetres Leonidas ◽  
Joseph Hayes ◽  
Atsushi Kato ◽  
Vassiliki Skamnaki ◽  
Demetra Chatzileontiadou ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glycaemic Control ◽  
Glycogen Phosphorylase ◽  
Glycogen Phosphorylase Inhibitors

Acyl Ureas as Human Liver Glycogen Phosphorylase Inhibitors for the Treatment of Type 2 Diabetes

2005 ◽  
Vol 48 (20) ◽  
pp. 6178-6193 ◽  
Author(s):  
Thomas Klabunde ◽  
K. Ulrich Wendt ◽  
Dieter Kadereit ◽  
Volker Brachvogel ◽  
Hans-Jörg Burger ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Human Liver ◽  
Glycogen Phosphorylase ◽  
Liver Glycogen ◽  
Glycogen Phosphorylase Inhibitors

Pentacyclic triterpenes, inhibitors of glycogen phosphorylase, as potential drugs for type 2 diabetes: X-ray crystallographic studies

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
SE Zographos ◽  
DD Leonidas ◽  
KM Alexacou ◽  
T Gimisis ◽  
JM Hayes ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glycogen Phosphorylase ◽  
X Ray ◽  
Pentacyclic Triterpenes

scholarly journals Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition

2016 ◽  
Vol 108 ◽  
pp. 444-454 ◽  
Author(s):  
David Goyard ◽  
Bálint Kónya ◽  
Aikaterini S. Chajistamatiou ◽  
Evangelia D. Chrysina ◽  
Jérémy Leroy ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glycogen Phosphorylase

Glycogen Phosphorylase as a Target for Type 2 Diabetes: Synthetic, Biochemical, Structural and Computational Evaluation of Novel N-acyl-N´-(β-D-glucopyranosyl) Urea Inhibitors

2015 ◽  
Vol 15 (23) ◽  
pp. 2373-2389 ◽  
Author(s):  
Anastassia Kantsadi ◽  
Vanessa Parmenopoulou ◽  
Dimitar Bakalov ◽  
Laura Snelgrove ◽  
George Stravodimos ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glycogen Phosphorylase ◽  
Computational Evaluation
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