I. Novel HCV NS5B polymerase inhibitors: Discovery of indole 2-carboxylic acids with C3-heterocycles

2011 ◽  
Vol 21 (18) ◽  
pp. 5336-5341 ◽  
Author(s):  
Gopinadhan N. Anilkumar ◽  
Charles A. Lesburg ◽  
Oleg Selyutin ◽  
Stuart B. Rosenblum ◽  
Qingbei Zeng ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Polymerase Inhibitors ◽  
Hcv Ns5b ◽  
Ns5b Polymerase

scholarly journals Discovery of N-Arylalkyl-3-hydroxy-4-oxo-3,4-dihydroquinazolin-2-carboxamide Derivatives as HCV NS5B Polymerase Inhibitors

ChemMedChem ◽  
2012 ◽  
Vol 7 (5) ◽  
pp. 850-860 ◽  
Author(s):  
Ravindra Ramesh Deore ◽  
Grace Shiahuy Chen ◽  
Pei-Teh Chang ◽  
Ting-Rong Chern ◽  
Shin-Yu Lai ◽  
...  
Keyword(s):  
Polymerase Inhibitors ◽  
Hcv Ns5b ◽  
Ns5b Polymerase

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides

2004 ◽  
Vol 14 (3) ◽  
pp. 793-796 ◽  
Author(s):  
Laval Chan ◽  
Sanjoy K. Das ◽  
T.Jagadeeswar Reddy ◽  
Carl Poisson ◽  
Mélanie Proulx ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Rna Replication ◽  
Subgenomic Rna ◽  
Hcv Ns5b ◽  
Ns5b Polymerase

QSAR study of C allosteric binding site of HCV NS5B polymerase inhibitors by support vector machine

2010 ◽  
Vol 15 (3) ◽  
pp. 645-653 ◽  
Author(s):  
Eslam Pourbasheer ◽  
Siavash Riahi ◽  
Mohammad Reza Ganjali ◽  
Parviz Norouzi
Keyword(s):  
Support Vector Machine ◽  
Binding Site ◽  
Support Vector ◽  
Qsar Study ◽  
Polymerase Inhibitors ◽  
Hcv Ns5b ◽  
Ns5b Polymerase

scholarly journals Identification and characterization of coumestans as novel HCV NS5B polymerase inhibitors

2008 ◽  
Vol 36 (5) ◽  
pp. 1482-1496 ◽  
Author(s):  
N. Kaushik-Basu ◽  
A. Bopda-Waffo ◽  
T. T. Talele ◽  
A. Basu ◽  
P. R. R. Costa ◽  
...  
Keyword(s):  
Polymerase Inhibitors ◽  
Hcv Ns5b ◽  
Ns5b Polymerase ◽  
Identification And Characterization

Discovery of 2-aminoisobutyric acid ethyl ester (AIBEE) phosphoramidate prodrugs for delivering nucleoside HCV NS5B polymerase inhibitors

2020 ◽  
Vol 30 (7) ◽  
pp. 126986
Author(s):  
John T. Randolph ◽  
Tongmei Li ◽  
A. Chris Krueger ◽  
Howard R. Heyman ◽  
Hui-Ju Chen ◽  
...  
Keyword(s):  
Ethyl Ester ◽  
Acid Ethyl Ester ◽  
Aminoisobutyric Acid ◽  
Polymerase Inhibitors ◽  
Hcv Ns5b ◽  
Ns5b Polymerase

QSAR and Molecular Docking Directed Synthesis and Preliminary Evaluation of Novel Non-Nucleoside HCV NS5B Polymerase Inhibitors

2017 ◽  
Vol 15 (1) ◽  
pp. 52-56
Author(s):  
Vaishali M. Patil ◽  
Neeraj Masand ◽  
Gurukumar K. R ◽  
Maksim Chudayeu ◽  
Satya Prakash Gupta ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Preliminary Evaluation ◽  
Polymerase Inhibitors ◽  
Directed Synthesis ◽  
Hcv Ns5b ◽  
Ns5b Polymerase
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