β-d-2′-α-F-2′-β-C-Methyl-6-O-substituted 3′,5′-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: A structure–activity relationship study

Activity Relationship ◽

Structure Activity ◽

Cyclic Phosphate ◽

Characterization and structure-activity relationship study of iminodipyridinopyrimidines as novel hepatitis C virus inhibitor

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.09.010 ◽

2017 ◽

Vol 140 ◽

pp. 65-73 ◽

Cited By ~ 2

Author(s):

Dong-Sik Park ◽

Eunji Jo ◽

Jihyun Choi ◽

MyungEun Lee ◽

Soohyun Kim ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Activity Relationship ◽

Virus Inhibitor ◽

Structure Activity ◽

Synthesis and structure-activity relationship study of new biaryl amide derivatives and their inhibitory effects against hepatitis C virus

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.114033 ◽

2021 ◽

pp. 114033

Author(s):

Yonghua Liu ◽

Jianrui Li ◽

Yuxi Gu ◽

Ling Ma ◽

Shan Cen ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Activity Relationship ◽

Inhibitory Effects ◽

Structure Activity ◽

Amide Derivatives ◽

Large-scale structure-activity relationship study of hepatitis C virus NS5B polymerase inhibition using SMILES-based descriptors

Molecular Diversity ◽

10.1007/s11030-015-9614-2 ◽

2015 ◽

Vol 19 (4) ◽

pp. 955-964 ◽

Cited By ~ 10

Author(s):

Apilak Worachartcheewan ◽

Virapong Prachayasittikul ◽

Alla P. Toropova ◽

Andrey A. Toropov ◽

Chanin Nantasenamat

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Large Scale ◽

Large Scale Structure ◽

Scale Structure ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study ◽

Ns5b Polymerase

A Quantitative Structure-Activity Relationship Study on a Few Series of Anti-hepatitis C Virus Agents

Medicinal Chemistry ◽

10.2174/1573406411208030491 ◽

2012 ◽

Vol 8 (3) ◽

pp. 491-504 ◽

Cited By ~ 1

Author(s):

Jonish Varshney ◽

Anjana Sharma ◽

Satya P. Gupta

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Quantitative Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

Structure–activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3/4A protease leading to the discovery of TMC435350

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2008.07.088 ◽

2008 ◽

Vol 18 (17) ◽

pp. 4853-4858 ◽

Cited By ~ 98

Author(s):

Pierre Raboisson ◽

Herman de Kock ◽

Åsa Rosenquist ◽

Magnus Nilsson ◽

Lourdes Salvador-Oden ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Activity Relationship ◽

Structure Activity ◽

ChemInform Abstract: Structure-Activity Relationship Study on a Novel Series of Cyclopentane-Containing Macrocyclic Inhibitors of the Hepatitis C Virus NS3/4H Protease Leading to the Discovery of TMC435350.

ChemInform ◽

10.1002/chin.200901182 ◽

2009 ◽

Vol 40 (1) ◽

Author(s):

Pierre Raboisson ◽

et al. et al.

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study ◽

Abstract Structure

Structure−Activity Relationship of Purine Ribonucleosides for Inhibition of Hepatitis C Virus RNA-Dependent RNA Polymerase

10.1021/jm030424e ◽

2004 ◽

Vol 47 (9) ◽

pp. 2283-2295 ◽

Cited By ~ 153

Author(s):

Anne B. Eldrup ◽

Charles R. Allerson ◽

C. Frank Bennett ◽

Sanjib Bera ◽

Balkrishen Bhat ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Rna Polymerase ◽

Activity Relationship ◽

Hepatitis C Virus Rna ◽

Rna Dependent Rna Polymerase ◽

Structure Activity ◽

Virus Rna ◽

Relationship Of

Imidazopyridazine Hepatitis C Virus Polymerase Inhibitors. Structure–Activity Relationship Studies and the Discovery of a Novel, Traceless Prodrug Mechanism

10.1021/jm401337x ◽

2013 ◽

Vol 57 (5) ◽

pp. 1964-1975 ◽

Cited By ~ 9

Author(s):

Martin Leivers ◽

John F. Miller ◽

Stephanie A. Chan ◽

Ryan Lauchli ◽

Sebastian Liehr ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Activity Relationship ◽

Polymerase Inhibitors ◽

Structure Activity

Benzimidazole Derivatives Bearing Substituted Biphenyls as Hepatitis C Virus NS5B RNA-Dependent RNA Polymerase Inhibitors: Structure−Activity Relationship Studies and Identification of a Potent and Highly Selective Inhibitor JTK-109

10.1021/jm060269e ◽

2006 ◽

Vol 49 (15) ◽

pp. 4721-4736 ◽

Cited By ~ 107

Author(s):

Shintaro Hirashima ◽

Takayoshi Suzuki ◽

Tomio Ishida ◽

Satoru Noji ◽

Shinji Yata ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Rna Polymerase ◽

Selective Inhibitor ◽

Activity Relationship ◽

Benzimidazole Derivatives ◽

Rna Dependent Rna Polymerase ◽

Polymerase Inhibitors ◽

Structure Activity

Discovery and Structure−Activity Relationship of P1−P3Ketoamide Derived Macrocyclic Inhibitors of Hepatitis C Virus NS3 Protease

10.1021/jm800940u ◽

2009 ◽

Vol 52 (2) ◽

pp. 336-346 ◽

Cited By ~ 32

Author(s):

Srikanth Venkatraman ◽

Francisco Velazquez ◽

Wanli Wu ◽

Melissa Blackman ◽

Kevin X. Chen ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of ◽

Ns3 Protease