Synthesis and biological evaluation of novel alkyl amide functionalized trifluoromethyl substituted pyrazolo[3,4-b]pyridine derivatives as potential anticancer agents

2013 ◽  
Vol 23 (21) ◽  
pp. 5893-5895 ◽  
Author(s):  
K. Chavva ◽  
S. Pillalamarri ◽  
V. Banda ◽  
S. Gautham ◽  
J. Gaddamedi ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Pyridine Derivatives ◽  
Synthesis And Biological Evaluation ◽  
Alkyl Amide

scholarly journals Design, synthesis and biological evaluation of novel pyridine derivatives as anticancer agents and phosphodiesterase 3 inhibitors

2009 ◽  
Vol 17 (16) ◽  
pp. 5974-5982 ◽  
Author(s):  
Ashraf H. Abadi ◽  
Tamer M. Ibrahim ◽  
Khaled M. Abouzid ◽  
Jochen Lehmann ◽  
Heather N. Tinsley ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Pyridine Derivatives ◽  
Design Synthesis ◽  
Phosphodiesterase 3 ◽  
Synthesis And Biological Evaluation

Design, synthesis, and biological evaluation of novel 3‐(thiophen‐2‐ylthio)pyridine derivatives as potential multitarget anticancer agents

2019 ◽  
Vol 352 (8) ◽  
pp. 1900024
Author(s):  
Jian‐Jun Xi ◽  
Ruo‐Yu He ◽  
Jian‐Kang Zhang ◽  
Zhao‐Bin Cai ◽  
Rang‐Xiao Zhuang ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Pyridine Derivatives ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

Synthesis and Biological Evaluation of 1,3,4-Thiadiazole Linked Phthalimide Derivatives as Anticancer Agents

2017 ◽  
Vol 14 (10) ◽  
Author(s):  
Zahra Rezaei ◽  
Setareh Moghimi ◽  
Rezvan Javaheri ◽  
Mehdi Asadi ◽  
Mohammad Mahdavi ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation

Design, Synthesis and Biological Evaluation of Tetrahydrodibenzo[b,g][1,8]napthyridinones as Potential Anticancer Agents and Novel Aurora Kinases Inhibitors

2021 ◽  
Vol 6 (14) ◽  
pp. 3444-3452
Author(s):  
Asha V. Chate ◽  
Pramod A. Tagad ◽  
Giribala M. Bondle ◽  
Aniket P. Sarkate ◽  
Shailee V. Tiwari ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
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Synthesis And Biological Evaluation

scholarly journals Molecular modeling study, synthesis and biological evaluation of combretastatin A-4 analogues as anticancer agents and tubulin inhibitors

MedChemComm ◽  
2018 ◽  
Vol 9 (2) ◽  
pp. 316-327 ◽  
Author(s):  
Yang Ping Quan ◽  
Li Ping Cheng ◽  
Tian Chi Wang ◽  
Wan Pang ◽  
Fan Hong Wu ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Anticancer Agents ◽  
Hepg2 Cells ◽  
Binding Mode ◽  
Biological Evaluation ◽  
Tubulin Inhibitors ◽  
Molecular Modeling Study ◽  
Synthesis And Biological Evaluation ◽  
Modeling Study

Compound 13a, more effective than CA-4 against HepG2 cells and tubulin, and the proposed binding mode for 13a.

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