Molecular modeling study, synthesis and biological evaluation of combretastatin A-4 analogues as anticancer agents and tubulin inhibitors

Compound 13a, more effective than CA-4 against HepG2 cells and tubulin, and the proposed binding mode for 13a.

Design, synthesis and biological evaluation of estradiol-PEG-linked platinum(II) hybrid molecules: Comparative molecular modeling study of three distinct families of hybrids

Steroids ◽

10.1016/j.steroids.2010.09.004 ◽

2011 ◽

Vol 76 (1-2) ◽

pp. 94-103 ◽

Cited By ~ 28

Author(s):

Josée Provencher-Mandeville ◽

Chhanda Debnath ◽

Sanat K. Mandal ◽

Valérie Leblanc ◽

Sophie Parent ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

Design Synthesis ◽

Hybrid Molecules ◽

Synthesis and biological evaluation of novel 6-nitro-5-substituted aminoquinolines as local anesthetic and anti-arrhythmic agents: molecular modeling study

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2005.02.050 ◽

2005 ◽

Vol 13 (9) ◽

pp. 3175-3183 ◽

Cited By ~ 25

Author(s):

Fatma E. Goda ◽

Alaa A.-M. Abdel-Aziz ◽

Hamdy A. Ghoneim

Keyword(s):

Molecular Modeling ◽

Local Anesthetic ◽

Biological Evaluation ◽

Synthesis and biological evaluation of new curcumin analogues as antioxidant and antitumor agents: Molecular modeling study

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2015.07.014 ◽

2015 ◽

Vol 101 ◽

pp. 584-594 ◽

Cited By ~ 19

Author(s):

Said M. Bayomi ◽

Hassan A. El-Kashef ◽

Mahmoud B. El-Ashmawy ◽

Magda N.A. Nasr ◽

Magda A. El-Sherbeny ◽

...

Keyword(s):

Molecular Modeling ◽

Antitumor Agents ◽

Biological Evaluation ◽

Curcumin Analogues ◽

Design, microwave assisted synthesis, and molecular modeling study of some new 1,3,4-thiadiazole derivatives as potent anticancer agents and potential VEGFR-2 inhibitors

Bioorganic Chemistry ◽

10.1016/j.bioorg.2021.104923 ◽

2021 ◽

Vol 112 ◽

pp. 104923

Author(s):

Saad R. Atta-Allah ◽

Asmaa M. AboulMagd ◽

Paula S. Farag

Keyword(s):

Molecular Modeling ◽

Anticancer Agents ◽

Microwave Assisted Synthesis ◽

Microwave Assisted ◽

Thiadiazole Derivatives ◽

Synthesis And Biological Evaluation

Design, Synthesis, and Biological Evaluation of Stable Colchicine-Binding Site Tubulin Inhibitors 6-Aryl-2-benzoyl-pyridines as Potential Anticancer Agents

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.1c00715 ◽

2021 ◽

Author(s):

Hao Chen ◽

Shanshan Deng ◽

Najah Albadari ◽

Mi-Kyung Yun ◽

Sicheng Zhang ◽

...

Keyword(s):

Binding Site ◽

Anticancer Agents ◽

Biological Evaluation ◽

Design Synthesis ◽

Tubulin Inhibitors ◽

Colchicine Binding Site ◽

Synthesis, biological evaluation and molecular modeling study of pyrazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents

Bioorganic Chemistry ◽

10.1016/j.bioorg.2014.05.004 ◽

2014 ◽

Vol 56 ◽

pp. 8-15 ◽

Cited By ~ 41

Author(s):

Ashish Kumar Tewari ◽

Ved Prakash Singh ◽

Pratima Yadav ◽

Garima Gupta ◽

Amit Singh ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

Pyrazole Derivatives ◽

Cox 2 ◽

Anti Inflammatory ◽

Cox 2 Inhibitors ◽

Thiazolo[4,5- d ]pyridazine analogues as a new class of dihydrofolate reductase (DHFR) inhibitors: Synthesis, biological evaluation and molecular modeling study

Bioorganic Chemistry ◽

10.1016/j.bioorg.2017.08.010 ◽

2017 ◽

Vol 74 ◽

pp. 228-237 ◽

Cited By ~ 8

Author(s):

Menna A. Ewida ◽

Dalal A. Abou El Ella ◽

Deena S. Lasheen ◽

Heba A. Ewida ◽

Yomna I. El-Gazzar ◽

...

Keyword(s):

Molecular Modeling ◽

Dihydrofolate Reductase ◽

Biological Evaluation ◽

New Class ◽

Dhfr Inhibitors ◽

Synthesis, biological evaluation and molecular modeling study of 2-amino-3,5-disubstituted-pyrazines as Aurora kinases inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2020.115351 ◽

2020 ◽

Vol 28 (5) ◽

pp. 115351 ◽

Cited By ~ 1

Author(s):

Yong-Xin Bo ◽

Rong Xiang ◽

Yu Xu ◽

Shu-Yi Hao ◽

Xing-Rong Wang ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

Aurora Kinases ◽

Thiadiazolodiazepine analogues as a new class of neuromuscular blocking agents: Synthesis, biological evaluation and molecular modeling study

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2016.09.096 ◽

2017 ◽

Vol 126 ◽

pp. 15-23 ◽

Cited By ~ 2

Author(s):

Hussein I. El-Subbagh ◽

Adel S. El-Azab ◽

Ghada S. Hassan ◽

Shahenda M. El-Messery ◽

Alaa A.-M. Abdel-Aziz ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

Neuromuscular Blocking ◽

Neuromuscular Blocking Agents ◽

New Class ◽

Blocking Agents ◽

Synthesis, biological evaluation and molecular modeling study of some new methoxylated 2-benzylthio-quinazoline-4( 3H )-ones as nonclassical antifolates

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2016.08.022 ◽

2016 ◽

Vol 26 (19) ◽

pp. 4815-4823 ◽

Cited By ~ 8

Author(s):

Shahenda M. El-Messery ◽

Ghada S. Hassan ◽

Mahmoud N. Nagi ◽

El-Sayed E. Habib ◽

Sarah T. Al-Rashood ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽