Design, synthesis and biological research of novel N-phenylbenzamide-4-methylamine acridine derivatives as potential topoisomerase I/II and apoptosis-inducing agents

2019 ◽  
Vol 29 (23) ◽  
pp. 126714 ◽  
Author(s):  
Bin Zhang ◽  
Zhende Dou ◽  
Zheng Xiong ◽  
Ning Wang ◽  
Shan He ◽  
...  
Keyword(s):  
Topoisomerase I ◽  
Biological Research ◽  
Design Synthesis ◽  
Acridine Derivatives ◽  
Apoptosis Inducing Agents

Design, synthesis, cytotoxicity and molecular modeling studies of some novel fluorinated pyrazole-based heterocycles as anticancer and apoptosis-inducing agents

2018 ◽  
Vol 23 (1) ◽  
pp. 165-181 ◽  
Author(s):  
Eman A. Fayed ◽  
Sally I. Eissa ◽  
Ashraf H. Bayoumi ◽  
Nirvana A. Gohar ◽  
Ahmed B. M. Mehany ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Design Synthesis ◽  
Modeling Studies ◽  
Molecular Modeling Studies ◽  
Apoptosis Inducing Agents

Design, synthesis and antiproliferative evaluation of fluorenone analogs with DNA topoisomerase I inhibitory properties

2013 ◽  
Vol 21 (22) ◽  
pp. 7125-7133 ◽  
Author(s):  
Chia-Chung Lee ◽  
Deh-Ming Chang ◽  
Kuo-Feng Huang ◽  
Chun-Liang Chen ◽  
Tsung-Chih Chen ◽  
...  
Keyword(s):  
Topoisomerase I ◽  
Dna Topoisomerase I ◽  
Dna Topoisomerase ◽  
Design Synthesis
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