Denosumab versus zoledronic acid (ZA) for the treatment of bone metastases: An integrated analysis of results from 2 randomized, double-blind, phase 3 trials

Bone ◽

10.1016/j.bone.2010.10.053 ◽

2011 ◽

Vol 48 (1) ◽

pp. S21

Author(s):

A. Lipton* ◽

A. Stopeck ◽

R. von Moos ◽

D. Henry ◽

G. Richardson ◽

...

Keyword(s):

Zoledronic Acid ◽

Bone Metastases ◽

Integrated Analysis ◽

Phase 3 ◽

Double Blind ◽

Analysis Of Results

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Incidence and outcomes of osteonecrosis of the jaw from an integrated analysis of three pivotal randomized double-blind, double-dummy phase 3 trials comparing denosumab and zoledronic acid for treatment of bone metastases in advanced cancer patients or myeloma

Bone ◽

10.1016/j.bone.2010.10.048 ◽

2011 ◽

Vol 48 (1) ◽

pp. S18-S19 ◽

Author(s):

J.E. Brown* ◽

C.H. Barrios ◽

I.J. Diel ◽

T. Facon ◽

K. Fizazi ◽

...

Keyword(s):

Zoledronic Acid ◽

Bone Metastases ◽

Cancer Patients ◽

Advanced Cancer ◽

Osteonecrosis Of The Jaw ◽

Integrated Analysis ◽

Advanced Cancer Patients ◽

Phase 3 ◽

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Results of a prospective, randomized, double-blind, double-dummy, Phase 3 study comparing denosumab with zoledronic acid for the treatment of breast cancer patients with bone metastases

Bone ◽

10.1016/j.bone.2010.01.078 ◽

2010 ◽

Vol 46 ◽

pp. S36-S37 ◽

Author(s):

Jean-Jacques Body ◽

Alison Stopeck ◽

Yasuhiro Fujiwara ◽

Allan Lipton ◽

Guenther Steger ◽

...

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Bone Metastases ◽

Cancer Patients ◽

Breast Cancer Patients ◽

Phase 3 ◽

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A meta-analysis of results from two randomized, double-blind studies of denosumab versus zoledronic acid (ZA) for treatment of bone metastases.

Journal of Clinical Oncology ◽

10.1200/jco.2010.28.15_suppl.9015 ◽

2010 ◽

Vol 28 (15_suppl) ◽

pp. 9015-9015 ◽

Author(s):

A. Lipton ◽

A. Stopeck ◽

R. von Moos ◽

D. H. Henry ◽

G. E. Richardson ◽

...

Keyword(s):

Zoledronic Acid ◽

Bone Metastases ◽

Meta Analysis ◽

Double Blind ◽

Analysis Of Results

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Results From a Phase 3 Randomized, Double-Blind, Double-Dummy Clinical Trial Comparing Denosumab with Zoledronic Acid for the Management of Bone Metastases in Patients with Advanced Solid Tumors or Multiple Myeloma

Bone ◽

10.1016/j.bone.2010.01.098 ◽

2010 ◽

Vol 46 ◽

pp. S44

Author(s):

Roger von Moos ◽

David Henry ◽

Saroj Vadhan-Raj ◽

Vania Hungria ◽

Andrew Spencer ◽

...

Keyword(s):

Clinical Trial ◽

Multiple Myeloma ◽

Zoledronic Acid ◽

Bone Metastases ◽

Solid Tumors ◽

Advanced Solid Tumors ◽

Phase 3 ◽

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AOS13 Denosumab versus zoledronic acid for the prevention of skeletal-related events in patients with bone metastases secondary to solid tumours: An integrated analysis of three phase 3 studies

European Journal of Cancer ◽

10.1016/j.ejca.2012.02.030 ◽

2012 ◽

Vol 48 ◽

pp. S8

Author(s):

A.T. Stopeck ◽

G. Richardson ◽

S. Siena ◽

A. Lipton ◽

J. Brown ◽

...

Keyword(s):

Zoledronic Acid ◽

Bone Metastases ◽

Solid Tumours ◽

Integrated Analysis ◽

Phase 3 ◽

Three Phase ◽

Skeletal Related Events

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Faculty Opinions recommendation of Pain outcomes in patients with advanced breast cancer and bone metastases: results from a randomized, double-blind study of denosumab and zoledronic acid.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717958301.793464607 ◽

2012 ◽

Author(s):

Nancy Lin ◽

Ines Vaz-Luis

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Advanced Breast Cancer ◽

Bone Metastases ◽

Advanced Breast ◽

Blind Study ◽

Double Blind Study ◽

Double Blind ◽

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Faculty Opinions recommendation of Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.9875966.793494170 ◽

2014 ◽

Author(s):

Thomas Flaig

Keyword(s):

Prostate Cancer ◽

Zoledronic Acid ◽

Bone Metastases ◽

Blind Study ◽

Double Blind Study ◽

Castration Resistant Prostate Cancer ◽

Double Blind ◽

Castration Resistant

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7004 ORAL Pain Outcomes in a Randomized Phase 3 Clinical Trial of Denosumab Vs Zoledronic Acid (ZA) in Patients With Solid Tumours and Bone Metastases

European Journal of Cancer ◽

10.1016/s0959-8049(11)71955-4 ◽

2011 ◽

Vol 47 ◽

pp. S485

Author(s):

L. Fallowfield ◽

R. von Moos ◽

D. Patrick ◽

C.S. Cleeland ◽

D.H. Henry ◽

...

Keyword(s):

Clinical Trial ◽

Zoledronic Acid ◽

Bone Metastases ◽

Solid Tumours ◽

Phase 3 ◽

Oral Pain ◽

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P3-16-07: Denosumab in Patients with Breast Cancer and Bone Metastases Previously Treated with Zoledronic Acid or Denosumab: Results from the 2-Year Open-Label Extension Treatment Phase of a Pivotal Phase 3 Study.

10.1158/0008-5472.sabcs11-p3-16-07 ◽

2011 ◽

Author(s):

AT Stopeck ◽

A Lipton ◽

M Martin ◽

J-J Body ◽

A Paterson ◽

...

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Bone Metastases ◽

Treatment Phase ◽

Phase 3 ◽

Pivotal Phase ◽

Open Label Extension ◽

Previously Treated

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Dexamethasone in the prophylaxis of radiation-induced pain flare after palliative radiotherapy for bone metastases: a double-blind, randomised placebo-controlled, phase 3 trial

The Lancet Oncology ◽

10.1016/s1470-2045(15)00199-0 ◽

2015 ◽

Vol 16 (15) ◽

pp. 1463-1472 ◽

Author(s):

Edward Chow ◽

Ralph M Meyer ◽

Keyue Ding ◽

Abdenour Nabid ◽

Pierre Chabot ◽

...

Keyword(s):

Bone Metastases ◽

Palliative Radiotherapy ◽

Phase 3 ◽

Double Blind ◽

Radiation Induced

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