A randomized, double-blind, placebo-controlled, single-dose study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of denosumab administered subcutaneously to postmenopausal Japanese women

Yuji Kumagai; Tomoko Hasunuma; Desmond Padhi

doi:10.1016/j.bone.2011.08.007

A randomized, double-blind, placebo-controlled, single-dose study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of denosumab administered subcutaneously to postmenopausal Japanese women

Bone ◽

10.1016/j.bone.2011.08.007 ◽

2011 ◽

Vol 49 (5) ◽

pp. 1101-1107 ◽

Cited By ~ 20

Author(s):

Yuji Kumagai ◽

Tomoko Hasunuma ◽

Desmond Padhi

Keyword(s):

Single Dose ◽

Japanese Women ◽

Pharmacokinetics And Pharmacodynamics ◽

Double Blind ◽

Single Dose Study ◽

Double Blind Placebo ◽

Dose Study

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Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alirocumab in Healthy Chinese Subjects: A Randomized, Double-Blind, Placebo-Controlled, Ascending Single-Dose Study

American Journal of Cardiovascular Drugs ◽

10.1007/s40256-020-00394-1 ◽

2020 ◽

Vol 20 (5) ◽

pp. 489-503

Author(s):

Haiyan Li ◽

Yudong Wei ◽

Zhenhua Yang ◽

Shuang Zhang ◽

Xiuxiu Xu ◽

...

Keyword(s):

Single Dose ◽

Pharmacokinetics And Pharmacodynamics ◽

Double Blind ◽

Single Dose Study ◽

Double Blind Placebo ◽

Dose Study ◽

Healthy Chinese ◽

Chinese Subjects

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561 Safety and pharmacokinetics of the now nucleoside polymerase inhibitor, HCV-796: Results of a randomized, double-blind, placebo-controlled, ascending single-dose study in healthy subjects

Journal of Hepatology ◽

10.1016/s0168-8278(06)80561-1 ◽

2006 ◽

Vol 44 ◽

pp. S208-S209 ◽

Cited By ~ 5

Author(s):

P. Chandra ◽

D. Raible ◽

L. Moyer ◽

D. Harper ◽

J. Speth ◽

...

Keyword(s):

Single Dose ◽

Healthy Subjects ◽

Double Blind ◽

Single Dose Study ◽

Double Blind Placebo ◽

Dose Study ◽

Polymerase Inhibitor

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A comparison of rofecoxib versus celecoxib in treating pain after dental surgery: A single-center, randomized, double-blind, placebo- and active-comparator-controlled, parallel-group, single-dose study using the dental impaction pain model

Clinical Therapeutics ◽

10.1016/s0149-2918(02)80059-5 ◽

2002 ◽

Vol 24 (10) ◽

pp. 1549-1560 ◽

Cited By ~ 47

Author(s):

Kerstin Malmstrom ◽

James R. Fricke ◽

Paul Kotey ◽

Barbara Kress ◽

Briggs Morrison

Keyword(s):

Single Dose ◽

Single Center ◽

Double Blind ◽

Single Dose Study ◽

Dental Surgery ◽

Pain Model ◽

Double Blind Placebo ◽

Active Comparator ◽

Parallel Group ◽

Dose Study

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A randomized, double-blind, placebo-controlled, ascending, single-dose study of a human monoclonal anti-FGF23 antibody (KRN23) in X-linked hypophosphatemia

Bone Abstracts ◽

10.1530/boneabs.3.pp90 ◽

2014 ◽

Author(s):

Thomas Carpenter ◽

Erik Imel ◽

Mary Ruppe ◽

Thomas Weber ◽

Mark Klausner ◽

...

Keyword(s):

Single Dose ◽

Double Blind ◽

Single Dose Study ◽

Double Blind Placebo ◽

Dose Study

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Faculty Opinions recommendation of Acute hemodynamic effects of riociguat in patients with pulmonary hypertension associated with diastolic heart failure (DILATE-1): a randomized, double-blind, placebo-controlled, single-dose study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718478272.793502540 ◽

2014 ◽

Author(s):

Jean-Luc Vachiery

Keyword(s):

Heart Failure ◽

Pulmonary Hypertension ◽

Single Dose ◽

Diastolic Heart Failure ◽

Hemodynamic Effects ◽

Double Blind ◽

Single Dose Study ◽

Double Blind Placebo ◽

Dose Study

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Alpha and Beta-Blockade and Beta-Stimulation in Raynaud's Syndrome: A Double-Blind, Placebo Controlled, Single Dose Study

Angiology ◽

10.1177/000331978503600404 ◽

1985 ◽

Vol 36 (4) ◽

pp. 219-225 ◽

Cited By ~ 8

Author(s):

Ton J.M. Cleophas ◽

Jan F.M. Fennis ◽

Albert van 't Laar

Keyword(s):

Single Dose ◽

Beta Blockade ◽

Double Blind ◽

Single Dose Study ◽

Double Blind Placebo ◽

Raynaud’S Syndrome ◽

Raynaud's Syndrome ◽

Dose Study

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P592 A phase 1, double-blind placebo-controlled single-dose study to determine the immune response to systemic and mucosal antigenic challenge in the presence of vedolizumab

Journal of Crohn s and Colitis ◽

10.1016/s1873-9946(13)60613-3 ◽

2013 ◽

Vol 7 ◽

pp. S248 ◽

Cited By ~ 5

Author(s):

T. Wyant ◽

T. Leach ◽

S. Sankoh ◽

Y. Wang ◽

J. Paolino ◽

...

Keyword(s):

Immune Response ◽

Single Dose ◽

Phase 1 ◽

Double Blind ◽

Single Dose Study ◽

Double Blind Placebo ◽

Antigenic Challenge ◽

Dose Study

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A Randomized, Double-Blind, Placebo- and Active-Controlled, Escalating Single-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Subcutaneous Eflapegrastim in Healthy Japanese and Caucasian Subjects

Drugs in R&D ◽

10.1007/s40268-021-00379-8 ◽

2022 ◽

Author(s):

Yoomin Jeon ◽

Nora Lee ◽

Seungjae Baek ◽

JaeDuk Choi ◽

Stanford Jhee ◽

...

Keyword(s):

Single Dose ◽

Double Blind ◽

Single Dose Study ◽

Double Blind Placebo ◽

Dose Study

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Acute hemoDynamic effects of rIociguat in patients with puLmonary hypertension Associated with diasTolic heart failurE (DILATE-1): A randomized, double-blind, placebo-controlled, single-dose study

European Heart Journal ◽

10.1093/eurheartj/eht309.p3321 ◽

2013 ◽

Vol 34 (suppl 1) ◽

pp. P3321-P3321 ◽

Cited By ~ 6

Author(s):

D. Bondermann ◽

I. Pretsch ◽

R. Steringer-Mascherbauer ◽

S. Rosenkranz ◽

C. Tufaro ◽

...

Keyword(s):

Heart Failure ◽

Pulmonary Hypertension ◽

Single Dose ◽

Diastolic Heart Failure ◽

Hemodynamic Effects ◽

Double Blind ◽

Single Dose Study ◽

Double Blind Placebo ◽

Dose Study

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Randomised, double-blind, placebo-controlled, cross-over single dose study of the bronchodilator duration of action of combination fluticasone furoate/vilanterol inhaler in adult asthma

Respiratory Medicine ◽

10.1016/j.rmed.2016.09.006 ◽

2016 ◽

Vol 119 ◽

pp. 115-121 ◽

Cited By ~ 8

Author(s):

Irene Braithwaite ◽

Mathew Williams ◽

Sharon Power ◽

Janine Pilcher ◽

Mark Weatherall ◽

...

Keyword(s):

Single Dose ◽

Fluticasone Furoate ◽

Double Blind ◽

Duration Of Action ◽

Single Dose Study ◽

Adult Asthma ◽

Double Blind Placebo ◽

Dose Study

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