scholarly journals Properties of Oscillating Electrical Pulse Induced Na/K Pump Current on Single Frog Skeletal Muscle

2018 ◽  
Vol 114 (3) ◽  
pp. 147a
Author(s):  
Pengfei Liang ◽  
Wei Chen
Author(s):  
Joachim R. Sommer ◽  
Nancy R. Wallace

After Howell (1) had shown that ruthenium red treatment of fixed frog skeletal muscle caused collapse of the intermediate cisternae of the sarcoplasmic reticulum (SR), forming a pentalaminate structure by obi iterating the SR lumen, we demonstrated that the phenomenon involves the entire SR including the nuclear envelope and that it also occurs after treatment with other cations, including calcium (2,3,4).From these observations we have formulated a hypothesis which states that intracellular calcium taken up by the SR at the end of contraction causes the M rete to collapse at a certain threshold concentration as the first step in a subsequent centrifugal zippering of the free SR toward the junctional SR (JSR). This would cause a) bulk transport of SR contents, such as calcium and granular material (4) into the JSR and, b) electrical isolation of the free SR from the JSR.


Author(s):  
A. V. Somlyo ◽  
H. Shuman ◽  
A. P. Somlyo

Electron probe analysis of frozen dried cryosections of frog skeletal muscle, rabbit vascular smooth muscle and of isolated, hyperpermeab1 e rabbit cardiac myocytes has been used to determine the composition of the cytoplasm and organelles in the resting state as well as during contraction. The concentration of elements within the organelles reflects the permeabilities of the organelle membranes to the cytoplasmic ions as well as binding sites. The measurements of [Ca] in the sarcoplasmic reticulum (SR) and mitochondria at rest and during contraction, have direct bearing on their role as release and/or storage sites for Ca in situ.


1990 ◽  
Vol 21 (6) ◽  
pp. 863-868 ◽  
Author(s):  
Péter P. Nánási ◽  
Tamás Kiss ◽  
Miklós Dankó ◽  
David A. Lathrop

1961 ◽  
Vol 44 (6) ◽  
pp. 1159-1164 ◽  
Author(s):  
Eugene M. Renkin

Using choline-methyl-C14 as a tracer, it has been shown that choline+ penetrates into the cells of resting frog skeletal muscle at a rate similar to that of Na+, and that it escapes from these cells much more slowly than does Na+. Some implications of these findings are discussed.


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