Effects of postnatal treadmill exercise on apoptotic neuronal cell death and cell proliferation of maternal-separated rat pups

2012 ◽  
Vol 34 (1) ◽  
pp. 45-56 ◽  
Author(s):  
Seung-Soo Baek ◽  
Tae-Won Jun ◽  
Ki-Jeong Kim ◽  
Mal-Soon Shin ◽  
Sun-Young Kang ◽  
...  
2007 ◽  
Vol 21 (5) ◽  
Author(s):  
Seung‐Soo Baek ◽  
Tae‐Won Jun ◽  
Mal‐Soon Shin ◽  
Il‐Gyu Ko ◽  
Ki‐Jeong Kim ◽  
...  

2016 ◽  
Vol 88 (suppl 1) ◽  
pp. 653-663 ◽  
Author(s):  
Dulce-Mariely Álvarez-Croda ◽  
Juan Santiago-García ◽  
Jesús S. Medel-Matus ◽  
Joel Martínez-Quiroz ◽  
Angel A. Puig-Lagunes ◽  
...  

The contribution of Interleukin-1β (IL-1β) to neuronal injury induced by status epilepticus (SE) in the immature brain remains unclear. The goal of this study was to determine the hippocampal expression of IL-1β and its type 1 receptor (IL-1RI) following SE induced by the lithium-pilocarpine model in fourteen-days-old rat pups; control animals were given an equal volume of saline instead of the convulsant. IL-1β and IL-1RI mRNA hippocampal levels were assessed by qRT-PCR 6 and 24 h after SE or control conditions. IL-1β and IL-1RI expression was detected in the dorsal hippocampus by immunohistochemical procedures; Fluoro-Jade B staining was carried out in parallel sections in order to detect neuronal cell death. IL-1β mRNA expression was increased 6 h following SE, but not at 24 h; however IL-1RI mRNA expression was unaffected when comparing with the control group. IL-1β and IL-1RI immunoreactivity was not detected in control animals. IL-1β and IL-1RI were expressed in the CA1 pyramidal layer, the dentate gyrus granular layer and the hilus 6 h after SE, whereas injured cells were detected 24 h following seizures. Early expression of IL-1β and IL-1RI in the hippocampus could be associated with SE-induced neuronal cell death mechanisms in the developing rat.


2013 ◽  
Vol 9 (6) ◽  
pp. 506-510 ◽  
Author(s):  
Jin-Hwan Yoon ◽  
Hee-Hyuk Lee ◽  
Eun-Surk Yi ◽  
Soon Gi Baek

2003 ◽  
Vol 352 (1) ◽  
pp. 33-36 ◽  
Author(s):  
Hee-Hyuk Lee ◽  
Hong Kim ◽  
Myoung-Hwa Lee ◽  
Hyun-Kyung Chang ◽  
Taeck-Hyun Lee ◽  
...  

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