The role of aromatic ring number in phenolic compound-conjugated chitosan injectables for sustained therapeutic antiglaucoma efficacy

2020 ◽  
Vol 231 ◽  
pp. 115770 ◽  
Author(s):  
Duc Dung Nguyen ◽  
Li-Jyuan Luo ◽  
Shingjiang Jessie Lue ◽  
Jui-Yang Lai
2019 ◽  
Vol 99 (11) ◽  
pp. 5176-5186 ◽  
Author(s):  
Yan Ma ◽  
Pei Wang ◽  
Ting Zhou ◽  
Zhijie Chen ◽  
Zhenxin Gu ◽  
...  

1998 ◽  
Vol 12 (3) ◽  
pp. 450-456 ◽  
Author(s):  
Liya E. Yu ◽  
Lynn M. Hildemann ◽  
Stephen Niksa
Keyword(s):  

2011 ◽  
Vol 94 (3) ◽  
pp. 213-217 ◽  
Author(s):  
Xiang-qing Wang ◽  
Xiao-bing Shi ◽  
Ran Au ◽  
Fu-shun Chen ◽  
Fang Wang ◽  
...  

2015 ◽  
Vol 15 (21) ◽  
pp. 31153-31196 ◽  
Author(s):  
L. Li ◽  
P. Tang ◽  
S. Nakao ◽  
C.-L. Chen ◽  
D. R. Cocker III

Abstract. Substitution of methyl groups onto the aromatic ring determines the SOA formation from the aromatic hydrocarbon precursor. This study links the number of methyl groups on the aromatic ring to SOA formation from aromatic hydrocarbons photooxidation under low NOx conditions (HC / NO > 10 ppb C : ppb). Aromatic hydrocarbons with increasing numbers of methyl groups are systematically studied. SOA formation from pentamethylbenzene and hexamethylbenzene are reported for the first time. A decreasing SOA yield with increasing number of methyl groups is observed. Linear trends are found in both f44 vs. f43 and O / C vs. H / C for SOA from aromatic hydrocarbons with zero to six methyl groups. An SOA oxidation state predictive method based on benzene is used to examine the effect of added methyl groups on aromatic oxidation under low NOx conditions. Further, the impact of methyl group number on density and volatility of SOA from aromatic hydrocarbons is explored. Finally, a mechanism for methyl group impact on SOA formation is suggested. Overall, this work suggests as more methyl groups are attached on the aromatic ring, SOA products from these aromatic hydrocarbons become less oxidized per mass/carbon.


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