Pericardial patch repair of the left atrioventricular valve in atrioventricular septal defect: long-term changes in the patch

2009 ◽  
Vol 18 (2) ◽  
pp. 119-122 ◽  
Author(s):  
Adriana Luk ◽  
Eric Ahn ◽  
Gursharan S. Soor ◽  
William G. Williams ◽  
Melitta Mezody ◽  
...  
1991 ◽  
Vol 17 (2) ◽  
pp. A154
Author(s):  
Ling Han ◽  
Sang C. Park ◽  
Jose A. Ettedgui ◽  
Elfriede Pahl ◽  
Lee B. Beerman ◽  
...  

1995 ◽  
Vol 5 (3) ◽  
pp. 230-237 ◽  
Author(s):  
Ling Han ◽  
Soon Ung Kang ◽  
Sang C. Park ◽  
Jose A. Ettedgui ◽  
William H. Neches

AbstractLong-term left atrioventricular valvar function was evaluated in 95 of 110 survivors following surgical repair of atrioventricular septal defect between 1975 and 1984. A common or complete form was present in 40 and a partitioned or partial form in 55 patients. The patients have been followed for three to 13 years with a mean of 8.3 years. Pulmonary arterial banding was performed in 17 patients with a common atrioventricular valve prior to complete repair. The left atrioventricular valvar regurgitation was evaluated by clinical examination, Doppler and/or angiography. Three patients required valvar replacement postoperatively. Previous pulmonary arterial banding, pulmonary hypertension or pulmonary-to-systemic flow ratio did not affect the incidence or severity of left atrioventricular valvar regurgitation postoperatively. In this series left atrioventricular valvar regurgitation increased in the early postoperative period but rarely progressed at late follow-up.


2020 ◽  
Vol 11 (6) ◽  
pp. 742-747
Author(s):  
Rinske J. IJsselhof ◽  
Saniyé D. R. Duchateau ◽  
Rianne M. Schouten ◽  
Martijn G. Slieker ◽  
Mark G. Hazekamp ◽  
...  

Background: Despite the improved outcome in complete atrioventricular septal defect (AVSD) repair, reoperations for left atrioventricular valve (LAVV) dysfunction are common. The aim of this study was to evaluate the effect of fresh untreated autologous pericardium for ventricular septal defect (VSD) closure on atrioventricular valve function and compare the results with the use of treated bovine pericardial patch material. Methods: Clinical and echocardiographic data were collected of patients with complete AVSD with their VSD closed with either untreated autologous pericardial or treated bovine pericardial patch material between January 1, 1996, and December 31, 2003. Evaluation closed in September 2019. Results: A total of 77 patients were analyzed (untreated autologous pericardial VSD patch: 59 [77%], treated bovine pericardial VSD patch: 18 [23%]). Median age at surgery was 3.6 (interquartile range [IQR]: 2.7-4.5) months, and median weight was 4.5 (IQR: 3.9-5.1) kg. Trisomy 21 was present in 70 (91%) patients. Median follow-up time was 17.5 (IQR: 12.6-19.8) years. Death <30 days occurred in two (3%) patients. Reinterventions occurred in eight patients (early [within 30 days] in two, early and late in one, and late in five), all in the autologous pericardium group. Log-rank tests showed no significant difference in mortality ( P = .892), LAVV reinterventions ( P = .228), or LAVV regurgitation ( P = .770). Conclusions: In AVSD, the VSD can safely be closed with either untreated autologous pericardium or xeno-pericardium. We found no difference in LAVV regurgitation or the need for reoperation between the two patches.


2021 ◽  
Vol 69 (S 03) ◽  
pp. e68-e75
Author(s):  
Stefanie Reynen ◽  
Hedwig H. Hövels-Gürich ◽  
Jaime F. Vazquez-Jimenez ◽  
Bruno J. Messmer ◽  
Joerg S. Sachweh

Abstract Objectives Patients with repaired complete atrioventricular septal defect (CAVSD) represent an increasing portion of grown-ups with congenital heart disease. For repair of CAVSD, the single-patch technique has been employed first. This technique requires division of the bridging leaflets, thus, among other issues, long-term function of the atrioventricular valves is of particular concern. Methods Between 1978 and 2001, 100 consecutive patients with isolated CAVSD underwent single-patch repair in our institution. Hospital mortality was 11%. Primary endpoints were clinical status, atrioventricular valve function, and freedom from reoperation in long term. Follow-up was obtained contacting the patient and/or caregiver, and the referring cardiologist. Results Eighty-three patients were eligible for long-term follow-up (21.0 ± 8.7, mean ± standard deviation [21.5; 2.1–40.0, median; min–max] years after surgical repair). Actual long-term mortality was 3.4%. Quality of life (QoL; self- or caregiver-reported in patients with Down syndrome) was excellent or good in 81%, mild congestive heart failure was present in 16%, moderate in 3.6% as estimated by New York Heart Association classification. Echocardiography revealed normal systolic left ventricular function in all cases. Regurgitation of the right atrioventricular valve was mild in 48%, mild–moderate in 3.6%, and moderate in 1.2%. The left atrioventricular valve was mildly stenotic in 15% and mild to moderately stenotic in 2%; regurgitation was mild in 54%, mild to moderate in 13%, and moderate in 15% of patients. Freedom from left atrioventricular-valve-related reoperation was 95.3, 92.7, and 89.3% after 5, 10, and 30 years, respectively. Permanent pacemaker therapy, as an immediate result of CAVSD repair (n = 7) or as a result of late-onset sick sinus syndrome (n = 5), required up to six reoperations in single patients. Freedom from pacemaker-related reoperation was 91.4, 84.4, and 51.5% after 5, 10, and 30 years, respectively. Conclusion Up to 40 years after single-patch repair of CAVSD, clinical status and functional results are promising, particularly, in terms of atrioventricular valve function. Permanent pacemaker therapy results in a life-long need for surgical reinterventions.


ESC CardioMed ◽  
2018 ◽  
pp. 793-799
Author(s):  
Michelle Carr

The clinical presentation of patients with an atrioventricular septal defect depends on whether a significant ventricular component is present. Repair is indicated in childhood. The major determinant of long-term outcome is the success of the left atrioventricular valve repair.


2017 ◽  
Vol 154 (6) ◽  
pp. 2019-2027 ◽  
Author(s):  
Edward Buratto ◽  
Xin Tao Ye ◽  
Christian P. Brizard ◽  
Johann Brink ◽  
Yves d’Udekem ◽  
...  

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