Optimizing Antimicrobial Therapy in Sepsis and Septic Shock

2009 ◽  
Vol 25 (4) ◽  
pp. 733-751 ◽  
Author(s):  
Anand Kumar
Keyword(s):  
Septic Shock ◽  
Antimicrobial Therapy ◽  
Sepsis And Septic Shock

Septic Shock

1992 ◽  
Vol 7 (2) ◽  
pp. 90-100 ◽  
Author(s):  
Margaret M. Parker ◽  
Mitchell P. Fink
Keyword(s):  
Septic Shock ◽  
Supportive Care ◽  
Antimicrobial Therapy ◽  
Clinical Manifestations ◽  
Sepsis Syndrome ◽  
Adjunctive Treatment ◽  
Cardiovascular Changes ◽  
The Past ◽  
Sepsis And Septic Shock ◽  
Very High

The incidence of sepsis and septic shock has been increasing dramatically over the past 10 years. Despite advances in antimicrobial therapy, the mortality of septic shock remains very high. We review the clinical manifestations of sepsis and septic shock and describe the cardiovascular manifestations. Pathophysiology of the cardiovascular changes is discussed, and mediators believed to be involved in the pathogenesis are reviewed. Management of septic shock is also discussed, including antimicrobial therapy, supportive care, and adjunctive treatment aimed at affecting the mediators involved in producing the sepsis syndrome.

Antimicrobial therapy for patients with severe sepsis and septic shock: An evidence-based review

2004 ◽  
Vol 32 (Supplement) ◽  
pp. S495-S512 ◽  
Author(s):  
Pierre-Yves Bochud ◽  
Marc Bonten ◽  
Oscar Marchetti ◽  
Thierry Calandra
Keyword(s):  
Septic Shock ◽  
Severe Sepsis ◽  
Antimicrobial Therapy ◽  
Evidence Based ◽  
Sepsis And Septic Shock

scholarly journals Impact of Appropriate Antimicrobial Therapy for Patients with Severe Sepsis and Septic Shock – A Quality Improvement Study

PLoS ONE ◽  
2014 ◽  
Vol 9 (11) ◽  
pp. e104475 ◽  
Author(s):  
Paula K. O. Yokota ◽  
Alexandre R. Marra ◽  
Marines D. V. Martino ◽  
Elivane S. Victor ◽  
Marcelino S. Durão ◽  
...  
Keyword(s):  
Septic Shock ◽  
Severe Sepsis ◽  
Quality Improvement ◽  
Antimicrobial Therapy ◽  
Sepsis And Septic Shock

Antimicrobial Therapy of Sepsis and Septic Shock—When Are Two Drugs Better Than One?

2011 ◽  
Vol 27 (2) ◽  
pp. e1-e27 ◽  
Author(s):  
Cybéle L. Abad ◽  
Anand Kumar ◽  
Nasia Safdar
Keyword(s):  
Septic Shock ◽  
Antimicrobial Therapy ◽  
Sepsis And Septic Shock ◽  
Better Than
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