Revealing the effects of microwell sizes on the crystal growth kinetics of active pharmaceutical ingredients by deep learning

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The crystal growth kinetics in the deeply undercooled Zr50Cu50 melt was studied with the electromagnetic levitation technique. The maximum growth rate umax was, for the first time, demonstrated in undercooled metal and alloy melts, and this allowed us to construct the complete profile of crystal growth kinetics in the whole undercooling region of Zr50Cu50 melt. In deep undercooling region near glass transition, the diffusion-controlled crystal growth mechanism accounted for the growth kinetics, while at lower undercooling the profile around umax remarkably differed from what the classical growth theory covers.


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