Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-Akt1 Complex Modulates Glioblastoma Therapy Sensitivity

Faculty Opinions recommendation of The extracellular matrix receptor discoidin domain receptor 1 regulates collagen transcription by translocating to the nucleus.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.736356510.793564138 ◽

2019 ◽

Author(s):

Christos Chatziantoniou ◽

Christos Chadjichristos

Keyword(s):

Extracellular Matrix ◽

Discovery and Optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as Novel Selective and Orally Bioavailable Discoidin Domain Receptor 1 (DDR1) Inhibitors

Journal of Medicinal Chemistry ◽

10.1021/jm301824k ◽

2013 ◽

Vol 56 (8) ◽

pp. 3281-3295 ◽

Cited By ~ 81

Author(s):

Mingshan Gao ◽

Lei Duan ◽

Jinfeng Luo ◽

Lianwen Zhang ◽

Xiaoyun Lu ◽

...

Keyword(s):

Orally Bioavailable ◽

Collagen receptors integrin alpha2beta1 and discoidin domain receptor 1 regulate maturation of the glomerular basement membrane and loss of integrin alpha2beta1 delays kidney fibrosis in COL4A3 knockout mice

Matrix Biology ◽

10.1016/j.matbio.2014.01.006 ◽

2014 ◽

Vol 34 ◽

pp. 13-21 ◽

Cited By ~ 38

Author(s):

Diana Rubel ◽

Jenny Frese ◽

Maria Martin ◽

Alexander Leibnitz ◽

Rainer Girgert ◽

...

Keyword(s):

Basement Membrane ◽

Glomerular Basement Membrane ◽

Knockout Mice ◽

Kidney Fibrosis ◽

Collagen Receptors ◽

Integrin Alpha2beta1 ◽

Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric receptors

The FASEB Journal ◽

10.1096/fasebj.14.7.973 ◽

2000 ◽

Vol 14 (7) ◽

pp. 973-981 ◽

Cited By ~ 27

Author(s):

Erik D. Foehr ◽

Anie Tatavos ◽

Eri Tanabe ◽

Simona Raffioni ◽

Silke Goetz ◽

...

Keyword(s):

Pc12 Cells ◽

Chimeric Receptors ◽

Erratum to: Discoidin Domain Receptor 1 is a therapeutic target for neurodegenerative diseases

Human Molecular Genetics ◽

10.1093/hmg/ddab082 ◽

2021 ◽

Author(s):

Alan J Fowler ◽

Michaeline Hebron ◽

Kaluvu Balaraman ◽

Wangke Shi ◽

Alexander A Missner ◽

...

Keyword(s):

Neurodegenerative Diseases ◽

Therapeutic Target ◽

Discoidin domain receptor 1: New star in cancer-targeted therapy and its complex role in breast carcinoma (Review)

Oncology Letters ◽

10.3892/ol.2018.7795 ◽

2018 ◽

Cited By ~ 5

Author(s):

Hui Jing ◽

Jingyuan Song ◽

Junnian Zheng

Keyword(s):

Targeted Therapy ◽

Breast Carcinoma ◽

Cancer Targeted Therapy ◽

Diabetic Vascular Calcification Mediated by the Collagen Receptor Discoidin Domain Receptor 1 via the Phosphoinositide 3-Kinase/Akt/Runt-Related Transcription Factor 2 Signaling Axis

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/atvbaha.118.311238 ◽

2018 ◽

Vol 38 (8) ◽

pp. 1878-1889 ◽

Cited By ~ 16

Author(s):

Marsel Lino ◽

Mark H. Wan ◽

Antonio S. Rocca ◽

David Ngai ◽

Navid Shobeiri ◽

...

Keyword(s):

Transcription Factor ◽

Vascular Calcification ◽

Signaling Axis ◽

Related Transcription Factor ◽

Phosphoinositide 3 Kinase ◽

Collagen Receptor ◽

Inhibition of Discoidin Domain Receptor 1 Prevents Stroma-Induced Peritoneal Metastasis in Gastric Carcinoma

Molecular Cancer Research ◽

10.1158/1541-7786.mcr-17-0710 ◽

2018 ◽

Vol 16 (10) ◽

pp. 1590-1600 ◽

Cited By ~ 12

Author(s):

Hyejin Jin ◽

In-Hye Ham ◽

Hye Jeong Oh ◽

Cheong A Bae ◽

Dakeun Lee ◽

...

Keyword(s):

Gastric Carcinoma ◽

Peritoneal Metastasis ◽

Role of periostin and discoidin domain receptor-1 (DDR1) in the regulation of cartilage degeneration and expression of MMP-13

Osteoarthritis and Cartilage ◽

10.1016/j.joca.2016.01.307 ◽

2016 ◽

Vol 24 ◽

pp. S156 ◽

Cited By ~ 1

Author(s):

M. Attur ◽

Q. Yang ◽

T. Kirsch ◽

S.B. Abramson

Keyword(s):

Cartilage Degeneration ◽

Structure of the Discoidin Domain Receptor 1 Extracellular Region Bound to an Inhibitory Fab Fragment Reveals Features Important for Signaling

Structure ◽

10.1016/j.str.2012.02.011 ◽

2012 ◽

Vol 20 (4) ◽

pp. 688-697 ◽

Cited By ~ 55

Author(s):

Federico Carafoli ◽

Marie Cathrin Mayer ◽

Kazushige Shiraishi ◽

Mira Anguelova Pecheva ◽

Lai Yi Chan ◽

...

Keyword(s):

Fab Fragment ◽

Extracellular Region ◽