scholarly journals RARE CASE OF SARCOMATOID CARCINOMA PRESENTING AS AN ANTERIOR MEDIASTINAL MASS

CHEST Journal ◽  
2021 ◽  
Vol 160 (4) ◽  
pp. A78-A79
Author(s):  
Kyomara Hernandez-Moya ◽  
Arnaldo Nieves-Ortiz ◽  
Ivanisse Ortiz Velez ◽  
Patricia Davila Cardona ◽  
Juan Garcia-Puebla ◽  
...  
Keyword(s):  
Rare Case ◽  
Mediastinal Mass ◽  
Sarcomatoid Carcinoma ◽  
Anterior Mediastinal Mass

Malignant Transformation of Metaplastic Thymoma into High-Grade Sarcomatoid Carcinoma: A Case Report

2021 ◽  
pp. 106689692110704
Author(s):  
Zheng Hua Piao ◽  
Jin Ping Chen ◽  
Hai Ren Chen ◽  
Xin Cheng Zhou
Keyword(s):  
Mediastinal Mass ◽  
Spindle Cell ◽  
Postoperative Radiotherapy ◽  
Sarcomatoid Carcinoma ◽  
Anterior Mediastinal Mass ◽  
High Grade ◽  
Ki 67 ◽  
Cellular Atypia ◽  
Spindle Cells ◽  
Cell Components

The correlation of histogenesis between metaplastic thymoma and thymic sarcomatoid carcinoma is unclear. We report a case of metaplastic thymoma transformed into high-grade sarcomatoid carcinoma. A 64  ×  54  ×  32 mm anterior mediastinal mass in a 61-year-old woman microscopically consisted mainly of classic metaplastic thymoma, with the center dominated by high-grade sarcomatoid carcinoma. In some areas, both epithelial and spindle cell components of the metaplastic thymoma showed increased cellular atypia, mitotic activity, and focal necrosis and gradually transformed into the polygonal/pleomorphic and spindle cell components of sarcomatoid carcinoma. Immunohistochemically, the characteristics of the polygonal/pleomorphic sarcomatoid cells were similar to those of the epithelial component of metaplastic thymoma, while the spindle sarcomatoid cells were more similar to the spindle cells component of metaplastic thymoma. The Ki-67 index was less than 5% in the metaplastic thymoma areas but up to 70% in the sarcomatoid carcinoma area. Radical operation and postoperative radiotherapy were performed. Multifocal relapses at the pleura occurred 13 months after surgery.

scholarly journals Anterior Mediastinal Mass in a Young Marijuana Smoker: A Rare Case of Small-Cell Lung Cancer

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Jiten P. Kothadia ◽  
Saurabh Chhabra ◽  
Alan Marcus ◽  
Michael May ◽  
Biren Saraiya ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Rare Case ◽  
Mediastinal Mass ◽  
Vena Cava ◽  
Small Cell ◽  
Mediastinal Lymphadenopathy ◽  
Anterior Mediastinal Mass ◽  
Small Cell Lung

The use of cannabis is embedded within many societies, mostly used by the young and widely perceived to be safe. Increasing concern regarding the potential for cannabis to cause mental health effects has dominated cannabis research, and the potential adverse respiratory effects have received relatively little attention. We report a rare case of 22-year-old man who presented with bilateral neck lymphadenopathy, fatigue, and sore throat without significant medical or family history. The patient had smoked one marijuana joint three times a week for three years but no cigarettes. Chest CT demonstrated a large anterior mediastinal mass compressing the superior vena cava and mediastinal lymphadenopathy. A final diagnosis of small-cell lung cancer was reached. Although rare, a small-cell lung cancer in this patient should alert the physician that cannabis smoking may be a risk factor for lung cancer.

scholarly journals Anesthetic Management in Anterior Mediastinal Pheochromocytoma Case

2020 ◽  
Author(s):  
Yücel Özgür
Keyword(s):  
Rare Case ◽  
Mediastinal Mass ◽  
Anesthetic Management ◽  
Tumor Resection ◽  
The Body ◽  
Anterior Mediastinal Mass ◽  
Open Thoracotomy ◽  
Anesthesia Management ◽  
History Of ◽  
Different Parts

Paraganglioma can be found in different parts of the body. In this case report, a rare case of anterior mediastinal paraganlioma was examined. Pheochromocytoma can pose problems in intraoperative anesthesia management. A 17-year-old male patient with an anterior mediastinal mass was first scheduled for thoracoscopic tumor resection, and then proceeded with open thoracotomy. The patient, who was diagnosed with preoperative pheochromocytoma, had a history of dual antihypertensive drug use. The patient, who showed an intraoperative labile course, had episodes of hypertension (270/140 mmHg) and tachycardia (200 bpm). Esmolol and nitroglycerin infusion was applied and intervened. Diagnosis of paraganglioma-related pheochromocytoma can be challenging. Risks can be minimized by making appropriate decisions and interventions before and during the operation.

A Case Report On a Rare Presentation Of Recurrent Breast Cancer As an Anterior Mediastinal Mass 9 Years After Mastectomy And Adjuvant Therapy

2019 ◽  
pp. 1-3
Keyword(s):  
Breast Cancer ◽  
Rare Case ◽  
Mediastinal Mass ◽  
Cancer Recurrence ◽  
Recurrent Breast Cancer ◽  
Anterior Mediastinal Mass ◽  
Rare Presentation ◽  
Regional Lymph Nodes ◽  
Stage Iii Breast Cancer ◽  
Recurrent Breast

The recurrence of breast cancer following treatment is about 13% for a patient with stage III breast cancer. The usual sites of recurrence are the breast, mastectomy scar, regional lymph nodes or distant metastasis such as lung, bone, lymph node, liver and pleura. We present a rare case of breast cancer recurrence presenting as an anterior mediastinal mass.

Solitary Fibrous Tumor of the Anterior Mediastinum: A Rare Extrapleural Neoplasm

2007 ◽  
Vol 93 (5) ◽  
pp. 508-510 ◽  
Author(s):  
Brian R Gannon ◽  
Carolyn D O'Hara ◽  
Kenneth Reid ◽  
Phillip A Isotalo
Keyword(s):  
Solitary Fibrous Tumor ◽  
Mediastinal Mass ◽  
Spindle Cell ◽  
Sarcomatoid Carcinoma ◽  
Anterior Mediastinal Mass ◽  
Peripheral Nerve Sheath Tumors ◽  
Solitary Fibrous Tumors ◽  
Spindle Cells ◽  
Complete Surgical Excision ◽  
Fibrous Tumor

Solitary fibrous tumors are uncommon spindle cell neoplasms originally thought to be restricted to the pleura. We describe a 62-year-old woman who presented with stridor and an anterior mediastinal mass. At thoracotomy, a 10.5 × 6.5 × 5.5 cm, circumscribed, firm mediastinal mass demonstrated no direct cardiac or pulmonary involvement. The tumor consisted of spindle cells organized in a patternless pattern with collagenous stroma and hemangiopericytoma-like vessels. Spindle cells were immunoreactive for CD34, CD99, desmin, vimentin and bcl-2 protein and a diagnosis of mediastinal solitary fibrous tumor was confirmed. The differential diagnosis of mediastinal solitary fibrous tumors is extensive and includes spindle cell thymoma, sarcomatoid carcinoma, malignant mesothelioma, inflammatory myofibroblastic tumor, peripheral nerve sheath tumors and various sarcomas. Despite their rarity in the mediastinum, solitary fibrous tumors can be recognized by their classic patternless morphology and immunophenotypic pattern. Their accurate classification is important, as solitary fibrous tumors are intermediate (rarely metastasizing) neoplasms that require complete surgical excision and long-term clinical follow-up for optimum therapy.

A rare case of anterior mediastinal mass caused by Brucella infection

2017 ◽  
Vol 25 (3) ◽  
pp. 222-225 ◽  
Author(s):  
Feridoun Sabzi ◽  
Reza Faraji
Keyword(s):  
Computed Tomography ◽  
Rare Case ◽  
Mediastinal Mass ◽  
Surgical Intervention ◽  
Artery Bypass ◽  
Median Sternotomy ◽  
High Fever ◽  
Anterior Mediastinal Mass ◽  
Brucella Infection ◽  
Upper Mediastinum

A previously healthy man, who had undergone coronary artery bypass 10 years earlier and had been diagnosed with brucellosis due to Brucella septicemia after Brucella arthritis, presented with chest pain and high fever. Anti- Brucella antibiotics were started, but after 4 weeks, his high fever remained. An infected mass was confirmed by computed tomography, and surgical intervention was performed via a median sternotomy. A large amount of thick pus gushed from an abscess in the upper mediastinum. The abscess cavity had a thick granulation wall, and cultured pus was positive for Brucella only. The patient responded well to antibiotic therapy.

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