Development and validation of a highly sensitive gas chromatographic–mass spectrometric screening method for the simultaneous determination of nanogram levels of fentanyl, sufentanil and alfentanil in air and surface contamination wipes

2004 ◽  
Vol 1035 (2) ◽  
pp. 249-259 ◽  
Author(s):  
Nadine F.J Van Nimmen ◽  
Hendrik A.F Veulemans
Keyword(s):  
Simultaneous Determination ◽  
Screening Method ◽  
Mass Spectrometric ◽  
Surface Contamination ◽  
Highly Sensitive ◽  
Development And Validation ◽  
Chromatographic Mass

Multiresidue Screening Method for Fresh Fruits and Vegetables with Gas Chromatographic/Mass Spectrometric Detection

1991 ◽  
Vol 74 (3) ◽  
pp. 554-565 ◽  
Author(s):  
Wenta Liao ◽  
Ton Joe ◽  
William G Cusick
Keyword(s):  
Aqueous Solution ◽  
Fruits And Vegetables ◽  
Capillary Column ◽  
Screening Method ◽  
Mass Spectrometric ◽  
Internal Standards ◽  
Average Percentage ◽  
Relative Standard ◽  
Chromatographic Mass

Abstract A gas chromatographic/mass spectrometric (GC/MS) screening method has been developed for the determination of pesticide residues in a variety of crop samples. Samples are extracted with acetonitrlle and partitioned with sodium chloride saturated aqueous solution. Targeted pesticide analytes are separated on a short, narrow bore capillary column, identified by electron ionization MS scanned from 100 to 400 amu, and quantitated by the monitoring of base ions and internal standards. The accuracy of the quantitative determination measured in terms of average percentage recovery of 143 compounds in 13 crop samples was 92% with a relative standard deviation of 22%.

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