Optimization of the chiral separation of a Ca-sensitizing drug on an immobilized polysaccharide-based chiral stationary phase

2005 ◽  
Vol 1083 (1-2) ◽  
pp. 96-101 ◽  
Author(s):  
Tong Zhang ◽  
Mireille Schaeffer ◽  
Pilar Franco
2015 ◽  
Vol 36 (9) ◽  
pp. 2379-2382 ◽  
Author(s):  
Daham Jeong ◽  
Hwanhee Kim ◽  
Someshwar D Dindulkar ◽  
Jae Yung Lee ◽  
Seunho Jung

2013 ◽  
Vol 7 (6) ◽  
pp. 546-550 ◽  
Author(s):  
Bhimireddy Venkata Rami Reddy ◽  
Nanduri Raman ◽  
Badam Sai Kumar ◽  
Chintala Rambabu

2003 ◽  
Vol 19 (8) ◽  
pp. 1157-1161 ◽  
Author(s):  
Guo-Sheng YANG ◽  
Piedad Parrilla VAZQUEZ ◽  
Antonia Garrido FRENICH ◽  
Jose L. Martinez VIDAL ◽  
Hassan Y. ABOUL-ENEIN

2020 ◽  
Vol 16 (3) ◽  
pp. 250-255
Author(s):  
Noura Kichou ◽  
Ismahan Rahou ◽  
Zaid M. Elamin ◽  
Khaled Sekkoum ◽  
Nasser Belboukhari ◽  
...  

Objective: Ten racemic 3,4-dihydropyrimidin-2(1H)-ones and 3,4-dihydropyrimidin- 2(1H)-thiones were separated by liquid chromatography on Chiralcel®OD-H column containing cellulose tris(3, 5-dimethylphenylcarbamate). Methods: The enantioseparation was carried out using Chiralcel®OD-H polysaccharide-type chiral stationary phase to resolve such enantiomers under normal-phase mode. Results: Complete separations of the 3,4-dihydropyrimidin-2(1H)-ones and 3,4-dihydropyrimidin- 2(1H)-thiones derivatives with good resolution (RS= 1.04-2.80) were achieved within a short time (10-15 min). Conclusion: An optimal baseline separation (Rs> 1.5) was achieved using Chiralcel®OD-H under normal-phase mode. Structure-retention relationships have also been discussed.


2018 ◽  
Vol 42 (5) ◽  
pp. 3526-3533 ◽  
Author(s):  
Jie Zhou ◽  
Bo Yang ◽  
Jian Tang ◽  
Weihua Tang

A cationic cyclodextrin (CD) clicked bilayer chiral stationary phase (CSP) was developed via click chemistry for chiral separations in multimode high-performance chromatography (HPLC).


2007 ◽  
Vol 846 (1-2) ◽  
pp. 119-123 ◽  
Author(s):  
Muzaffar Khan ◽  
Balaji Viswanathan ◽  
D. Sreenivas Rao ◽  
Rajasekhar Reddy

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