RIGHT VENTRICULAR DIMENSIONS AND RISK OF SUSTAINED VENTRICULAR ARRHYTHMIAS IN PATIENTS WITH CONTINUOUS FLOW DURABLE VENTRICULAR ASSIST DEVICES

2016 ◽  
Vol 32 (10) ◽  
pp. S288
Author(s):  
B. Plourde ◽  
R.R. Satish ◽  
J. Howlett ◽  
D.L. Isaac ◽  
N.C. Sharma
Keyword(s):  
Right Ventricular ◽  
Continuous Flow ◽  
Ventricular Arrhythmias ◽  
Ventricular Assist Devices ◽  
Ventricular Assist ◽  
Assist Devices ◽  
Ventricular Dimensions

Results of primary biventricular support: an analysis of data from the EUROMACS registry

2019 ◽  
Vol 56 (6) ◽  
pp. 1037-1045 ◽  
Author(s):  
Juliane Vierecke ◽  
Brigitta Gahl ◽  
Theo M M H de By ◽  
Herwig Antretter ◽  
Friedhelm Beyersdorf ◽  
...  
Keyword(s):  
Heart Failure ◽  
Adverse Events ◽  
Right Ventricular ◽  
Continuous Flow ◽  
Left Ventricular ◽  
Ventricular Assist Devices ◽  
Short Term ◽  
Ventricular Assist ◽  
Assist Devices

Abstract OBJECTIVES The purpose of this study was to describe pre- and postoperative data from the EUROMACS registry with regard to indications, for and survival and complication rates of patients with primary continuous flow and pulsatile biventricular long-term assist devices (BiVADs) versus total artificial hearts (TAHs) or left ventricular assist devices (LVADs) + short-term right ventricular assist device (RVAD) implants. METHODS We investigated patients who received implants between 1 January 2011 and 21 October 2017. Clinical baseline information about comorbidities, laboratory results, medical and device therapies and echocardiographic, haemodynamic and right ventricle (RV) parameters were evaluated along with the rates of deaths and complications. RESULTS A total of 413 of 3282 patients (12.5%) needed a biventricular pump. We investigated 37 long-term BiVADs, 342 LVAD + short-term RVAD implants and 34 TAHs. Minor differences were found in the baseline characteristics of our population, which had an overall high morbidity profile. The 1-year survival rate was 55% for patients with a continuous flow BiVAD; 52% for patients with an LVAD + short-term RVAD; 37% for patients with pulsatile BiVADs; and 36% for patients with a TAH. No statistical difference was observed among the groups. Over 50% of patients with BiVAD support were classified as INTERMACS profiles 1 and 2. The percent of patients with ambulatory heart failure (INTERMACS 4‒7) undergoing BiVAD implants was modest at <15%. No patients with a pulsatile BiVAD (n = 15) or a TAH (n = 34) were implanted as destination therapy, but 27% of the patients with continuous flow BiVADs (n = 6) and 23% of the patients with LVAD + short-term RVAD (n = 342) were implanted as ‘destination’. The adverse events profile remained high, with no significant difference among pump types. The right ventricular stroke work index and right heart failure scores indicated poor RV function in all groups. After 3 months of LVAD + short-term RVAD support, 46.7% still required ongoing support, and only 18.5% were weaned from RVAD support; 33.1% died. CONCLUSIONS The mortality rate after BiVAD support was high. Survival rates and adverse events were statistically not different among the investigated groups. In the future, composite study end points examining quality of life and adverse events beyond survival may help in shared decision-making prior to general mechanical circulatory support, particularly in patients with BiVAD implants.

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