Prurigo, pruritic folliculitis, and atopic eruption of pregnancy: Facts and controversies

2016 ◽  
Vol 34 (3) ◽  
pp. 392-400 ◽  
Author(s):  
Maria Magdalena Roth ◽  
Patricia Cristodor ◽  
George Kroumpouzos
Keyword(s):  
Atopic Eruption Of Pregnancy

scholarly journals Dermatoses Of Pregnancy: A Retrospective Cohort Study In Spain

2019 ◽  
Author(s):  
M. Gomes Ferreira ◽  
D. Bancalari Diaz ◽  
Á. De Dios Velázquez ◽  
J. Cañueto
Keyword(s):  
Mediterranean Population ◽  
Pemphigoid Gestationis ◽  
Skin Changes ◽  
Inflammatory Dermatoses ◽  
Polymorphic Eruption Of Pregnancy ◽  
Multiple Gestations ◽  
Nulliparous Women ◽  
Atopic Eruption Of Pregnancy ◽  
Dermatologic Disease ◽  
Dermatoses Of Pregnancy

Abstract Background: Dermatoses of pregnancy (DP) is a heterogeneous group of pruritic inflammatory dermatoses that occur exclusively during pregnancy and/or puerperium. The objective of this study was to assess the specific DP and non-specific dermatoses in a Mediterranean population living in Spain. Methods: This five-year retrospective study included 79 pregnant women with dermatologic disease from a total of 10533 pregnancies. Obstetric and clinical variables were assessed. Physiological skin changes of pregnancy were excluded. Those dermatoses that may also be observed beyond pregnancy and puerperium were also excluded. Results: The mean age was 32 years. The most common DP were: Polymorphic eruption of pregnancy (PEP) – 36%, Atopic eruption of pregnancy (AEP) – 26%, Intrahepatic cholestasis of pregnancy (ICP) – 8% and Pemphigoid gestationis (PG) – 6%. The other 24% presented non-specific dermatoses. Only in one case of PG the newborn showed comorbidity. Discussion: Multiple gestations were observed in 10,3% of PEP, in association with a rapid abdominal distention. In AEP, there was a predominance of nulliparous women in the second trimester of pregnancy, an atopic dermatitis background and female newborns. In PG, there was a majority of nulliparous in the second and third trimesters. PG was the only dermatoses associated to comorbidity of the newborn. In ICP, all patients had pruritus in the palms along with excoriations, with predominance of nulliparous and multiple gestations.

Histopathological Diagnosis of Atopic Eruption of Pregnancy and Polymorphic Eruption of Pregnancy

2014 ◽  
Vol 36 (10) ◽  
pp. 812-821 ◽  
Author(s):  
Cesare Massone ◽  
Lorenzo Cerroni ◽  
Neureiter Heidrun ◽  
Alexandra M. G. Brunasso ◽  
Enrico Nunzi ◽  
...  
Keyword(s):  
Histopathological Diagnosis ◽  
Polymorphic Eruption Of Pregnancy ◽  
Atopic Eruption Of Pregnancy

scholarly journals Dermatoses Específicas da Gravidez

2013 ◽  
Vol 26 (5) ◽  
pp. 593
Author(s):  
Vera Teixeira ◽  
Inês Coutinho ◽  
Rita Gameiro ◽  
Ricardo Vieira ◽  
Margarida Gonçalo
Keyword(s):  
Intrahepatic Cholestasis ◽  
Skin Diseases ◽  
Intrahepatic Cholestasis Of Pregnancy ◽  
Vascular Changes ◽  
Safe Treatment ◽  
Timely Diagnosis ◽  
Polymorphic Eruption Of Pregnancy ◽  
Atopic Eruption Of Pregnancy ◽  
Cholestasis Of Pregnancy

During pregnancy immunological, metabolic, hormonal and vascular changes occur, and can cause specific skin diseases. The specificdermatoses of pregnancy have undergone numerous changes in nomenclature and classification, partly due to advances in the knowledge of the pathogenesis of these skin diseases. Currently the following diseases are considered specific dermatoses of pregnancy:pemphigoid gestations, polymorphic eruption of pregnancy, intrahepatic cholestasis of pregnancy and atopic eruption of pregnancy. Timely diagnosis and specific and safe treatment are essential to prevent complications which, although rare, may be associated with significant maternal-fetal comorbidity.

scholarly journals Dermatological Diseases Associated with Pregnancy: Pemphigoid Gestationis, Polymorphic Eruption of Pregnancy, Intrahepatic Cholestasis of Pregnancy, and Atopic Eruption of Pregnancy

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Christine Sävervall ◽  
Freja Lærke Sand ◽  
Simon Francis Thomsen
Keyword(s):  
Intrahepatic Cholestasis ◽  
Clinical Importance ◽  
Intrahepatic Cholestasis Of Pregnancy ◽  
Pemphigoid Gestationis ◽  
Polymorphic Eruption Of Pregnancy ◽  
Atopic Eruption Of Pregnancy ◽  
Considerable Morbidity ◽  
Dermatoses Of Pregnancy ◽  
Cholestasis Of Pregnancy ◽  
Pregnant Mothers

Dermatoses unique to pregnancy are important to recognize for the clinician as they carry considerable morbidity for pregnant mothers and in some instances constitute a risk to the fetus. These diseases include pemphigoid gestationis, polymorphic eruption of pregnancy, intrahepatic cholestasis of pregnancy, and atopic eruption of pregnancy. This review discusses the pathogenesis, clinical importance, and management of the dermatoses of pregnancy.

scholarly journals Dermatoses of pregnancy. A prospective study from Benghazi, Libya

2019 ◽  
Vol 3 (6) ◽  
pp. 166
Author(s):  
Safa Suleman Elfaituri
Keyword(s):  
Prospective Study ◽  
Intrahepatic Cholestasis ◽  
Skin Diseases ◽  
Fetal Mortality ◽  
Intrahepatic Cholestasis Of Pregnancy ◽  
Pemphigoid Gestationis ◽  
Fetal Risk ◽  
Atopic Eruption Of Pregnancy ◽  
A Prospective Study ◽  
Cholestasis Of Pregnancy

Introduction: Cutaneous findings in pregnancy can be physiologic, coincidental, alterations in pre-existing skin diseases or pregnancy specific. The Pregnancy dermatoses can impact the health of the pregnant woman and the fetus Objectives: Our objective was to determine the spectrum of skin disease associated with pregnancy and to identify the various types of pregnancy specific dermatoses and their fetal risk. Materials & methods: A prospective study was performed at dermatology out-patient department of Jumhoria hospital and Ibn Sina polyclinic, Benghazi-Libya over a period of 2 years. A total of 200 pregnant women presented with dermatological complaint were included. History, skin examination, and relevant investigations were performed. The patients with pregnancy specific dermatoses were followed up till delivery and the pregnancy outcome was recorded. The results were analyzed using SPSS. Results: Mean age was 32 years, 62% was multigravidae and 54% of pregnancy dermatoses occurred during third trimester. The highest number of cases presented with coincidental or preexisting diseases (71%); infections (34%), pre-existing skin diseases included eczema (13%), acne vulgaris (4%) and psoriasis (3%) Hyperpigmentation and strieagravidarum represented the main physiological changes (17%). Specific pregnancy dermatoses were present in 12%, these were intrahepatic cholestasis of pregnancy (4%), atopic eruption of pregnancy (3%), pemphigoid gestationis (3%) and polymorphic eruption of pregnancy (2%). Fetal complications including fetal mortality were reported with pemphigoid gestationis (30%) and intrahepatic cholestasis of pregnancy (25%). Conclusions: This study provides important data on the spectrum of pregnancy dermatoses in Libyan patients. Most of the reported pregnancy dermatoses were benign with no adverse effect on the fetus. Pemphigoid gestationis and intrahepatic cholestasis of pregnancy can be a source of significant fetal risk. To the best of our knowledge this is the first study carried out on pregnancy dermatoses in Benghazi, Libya.

scholarly journals Specific dermatoses of pregnancy: New classification and differential diagnosis

2008 ◽  
Vol 61 (11-12) ◽  
pp. 586-590 ◽  
Author(s):  
Ljiljana Medenica ◽  
Sonja Vesic ◽  
Jelica Sretenovic-Vukicevic
Keyword(s):  
Intrahepatic Cholestasis ◽  
Elevated Serum ◽  
Direct Immunofluorescence ◽  
Intrahepatic Cholestasis Of Pregnancy ◽  
Pemphigoid Gestationis ◽  
Polymorphic Eruption Of Pregnancy ◽  
Atopic Eruption Of Pregnancy ◽  
Maternal Quality Of Life ◽  
Dermatoses Of Pregnancy ◽  
Cholestasis Of Pregnancy

Introduction The specific dermatoses of pregnancy represent heterogeneous group of pruritic skin disorders that occur exclusively in pregnancy. Specific Dermatoses of pregnancy The updated classification proposed subdividing specific dermatoses of pregnancy into four main categories: 1. atopic eruption of pregnancy; 2. polymorphic eruption of pregnancy; 3. pemphigoid gestationis; 4. intrahepatic cholestasis of pregnancy. Severe pruritius, which is the main symptom in all 4 entities, can impair maternal quality of life. Significant maternal risks are not associated with specific dermatoses of pregnancy; however, pemphigoid gestationis and intrahepatic cholestasis of pregnancy are associated with fetal risks. Conclusion Pathognomonic laboratory tests are not available, except direct immunofluorescence which is diagnostic of pemphigoid gestationis and elevated serum level of bile acids of intrahepatic cholestasis of pregnancy. Characteristic clinical features provide discrimination between polymorphic eruption of pregnancy and atopic eruption of pregnancy.

scholarly journals A study of dermatoses in antenatal patients attending tertiary care centre

2021 ◽  
Vol 7 (2) ◽  
pp. 239
Author(s):  
Valay Desai ◽  
Avani C. Patel ◽  
Anjum M. Momin ◽  
Jignesh B. Vaishnani
Keyword(s):  
Structural Changes ◽  
Skin Diseases ◽  
Tertiary Care ◽  
Significant Risk ◽  
Well Being ◽  
Striae Distensae ◽  
Tertiary Care Centre ◽  
Cutaneous Lesions ◽  
Cross Sectional ◽  
Atopic Eruption Of Pregnancy

<p><strong>Background: </strong>Pregnancy produces many cutaneous changes which can be either physiological, alteration in pre-existing skin diseases or development of dermatoses which are specific to pregnancy which occur due to the production of a number of proteins and steroid hormones by the fetoplacental unit and maternal pituitary, thyroid and adrenals. Patient’s concern may range from cosmetic appearance to potential effects on mother and fetus. Aims and objectives: Study was undertaken to observe physiological and pathological skin changes in different gravidae and trimesters of pregnancy.</p><p><strong>Methods: </strong>A cross sectional study performed after institutional ethics committee clearance. Total 205 pregnant females were enrolled in study by simple random sampling. Complete history, clinical examination and relevant investigations were done. Patients were treated accordingly. Data was analysed by application of descriptive analysis, Mean and SD.</p><p><strong>Results: </strong>In physiological changes, linea nigra was the most common, followed by striae distensae. Pigmentary changes were found more commonly in 2<sup>nd</sup> trimester while vascular and structural changes were commoner in 3<sup>rd</sup> trimester. In dermatoses affected by pregnancy, fungal infection was most common followed by viral infections and acne which were most commonly seen in 2<sup>nd</sup> trimester. Polymorphic eruption of pregnancy was most common among pregnancy specific dermatoses followed by pruritus gravidarum which were more commonly noted in the 3<sup>rd</sup> trimester. Atopic eruption of pregnancy was common in 2<sup>nd</sup> trimester. As study was cross sectional, disease progression and treatment outcome could not be observed.</p><p><strong>Conclusions: </strong>Cutaneous lesions<strong> </strong>may range from common, benign changes termed physiological or more severe, posing significant risk to mother and child. Timely diagnosis and prompt treatment is essential for improving maternal and fetal well-being and prognosis and to minimize their morbidity.<strong></strong></p>

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