Grover’s disease: a rare bullous dermatosis spontaneously regressing

Grover's diseaseis an itchy acantholytic disorder occurring on the trunk of middle-aged men. It is a transient dermatosis of unknown cause manifesting clinically as a papular skin eruption located usually on the anterior chest and abdomen and histologically with dyskeratosis and acantholysis. This disease has occasionally been reported in patients with chronic renal failure, some infections, hematological malignancies, and many other anomalies. We report herein a new case of Grover's disease that developed in a female patient after a fever episode.

Mandible: evaluation of its morphology, aging process and sexual dimorphism for aesthetic treatment purpose

The mandible is the most important bone structure of the facial makeup. Its morphology differs with respect to genetic factors, sexual dimorphism, and age. Among its particular characteristics is the ability to adapt with its counterpart, the base of the skull, conferring a dynamic quality of this bone, by the mechanism of constant remodeling. In order to understand the involvement of the mandible in the evaluation of the lower third of the face, a fractional analysis of its parts is necessary considering morphological parameters of the mandibular angle. The purpose of this study is to demonstrate the importance of the mandible as an instrument in the analysis of the lower third of the face, allowing the accomplishment of aesthetic treatment, respecting the individual characteristics.

Subcutaneous radiofrequency: prospective pilot study on safety and efficacy in face chrono-ageing treatment

Objective: to evaluate the efficacy, safety and tolerance of the face aging treatment using subcutaneous radiofrequency in patients with mild, moderate e severe ptosis of the middle face. Material and methods: prospective data from patients treated with subcutaneous radiofrequency. Patients underwent two treatment session carried out by the same surgeon. The principal efficacy criterion was the assessment of depth reduction of the naso-labial fold and malar prominence’s restoration after 3 and 6 months, the evaluation of the Global Aesthetic Improvement Scale by the patients and an outside procedure surgeon was the second criteria. Safety and tolerance were evaluated through observed side effects. Result: A total of 30 patients, 27 women and 3 men with a mean age of 53 years underwent subcutaneous radiofrequency procedure. Depth’s reduction of the naso-labial fold and malar prominence’s restoration was observed in the majority of all case, associated to the patient e medical satisfaction. Transitory adverse effects, commonly for cosmetic procedure e.g erythema, edema was not observed. One patient had post procedure hematoma. No serious adverse effects such as burning or scars were reported. Conclusion: This prospective pilot data confirmed that subcutaneous radiofrequency is a safe and effective in improvement in skin laxity. Patients’ satisfaction was high. Although this treatment cannot substitute surgical procedure, it might prolong the time to the first surgical facial lift. Further confirmation investigation should be performed.

Case review: respective treatment modalities with the use of combined ingredients to address acne prone skin

Acne is an inflammatory skin disease which affects the pilosebaceous units of the skin. It can have profound psychological effects and can leave the patient with severe skin scarring. There are four well-recognized pathological factors responsible for acne which is also the target for acne therapy. In this case review, different treatment options are outlined, including topical and systemic treatments. A safer treatment option other than the use of antibiotics or oral retinoids, the use of complementary and alternative medicines (CAM) for treating acne was discussed as well as the affect of maintaining a healthy lifestyle. Acne has been extensively researched with regards to the disease mechanism as well as treatment options. However, due to the increasing resistance of acne prone bacteria towards the available antibiotics, there is a need for new treatment methods. Systemic medication also influences the liver and therefore our hypothesis was to investigate a preventative, safer, and risk-free approach. Additionally, the lack of sufficient evidence on the efficacy of CAM therapies makes it necessary for researchers to investigate these treatment options further. Biomedical Emporium comprise of respective and well-known ingredients frequently used within the medical aesthetic industry to address the concerns of acne. We have investigated a wide array of ingredients used in patient treatment protocols and the favourable effect thereof on the use of acne. We discuss the combined use of topical treatment protocols as well as the use of ingredients for systemic use.

Acquired lymphangioma circumscriptum of the vulva treated with ablative radiofrequency

(LC) is a benign disorder involving the lymphatic system of skin and subcutaneous tissue. A case of acquired LC of the vulva in a57-year-old woman with a 10 -15 year history of lymphoedema of the left leg and vulvar lesions (vesicles and papulovesicles) following cervical cancer operation and subsequent radio therapy is presented. The patient was treated with ablative radiofrequency and was free of lesions for 6 months.

Clinical effects of atopical twin-serum (aqua phase and lipo phase) on skin radiance and wrinkle depth: role of active ingredients and delivery optimisation

ntroduction: Skin appearance plays as an important moderator in human daily social interactions so everyday we see new and innovative solutions to fight the signs of aging. One of the important parameters of skin appearance is skin complexion radiance as it could Reflect the general health, emotional State, hormonal status, nutrition, fatigue, age or environmental factors such as smoking, drinking, seasons, etc. Objective: The objective of the study was to evaluate the effect of the daily application of a bi-phasic serum during 8 weeks on the skin radiance and skin aging parameters of healthy women with dull complexion. Subjects and method: 30 healthy female volunteers of 35 to 60 years old were enrolled in the study. The activated product (aquaserum and liposerum) were applied to the face, twice a day for 8 weeks. The evaluation was performed on T0 and T8 weeks by measuring the skin radiance using clinical scoring C.L.B.T.TM and Glossymeter® GL200, Crow’s feet wrinkles by Bazin visual perioral scale, skin elasticity by Cutometer® SM575, and also the subject’s self-assessment. Results: All 30 subjects finished the study without any serious adverse events. The results revealed a significant improvement in all C.L.B.T.TM indicators presenting skin radiance through an increase of Luminosity (29%), Transparency (28%), Brightness (27%) (p=0.001) while a decrease of Pink Red (38%), Olive (31%), Beige (30%), Light Pink (21%) parameters (p<0.001).For skin relief, statistical analyses revealed a significant decrease of wrinkles’ depth evaluated by clinical scoring (9%, p=0.003). For the elasticity, an improvement which tends to be significant (0.462±0.098 at T0 and 0.506±0.111 at T8 weeks; p=0.06) for the Ur/Ue parameter, was observed.After 8 weeks of topical application of Perfectil® Twin-Serum, the subjects significantly found that their skin is less dull (p=0.002), less red (p=0.002), with less spots (p=0.044), less sagging (p=0.002) and less wrinkles (p=0.002). Conclusion: The results observed in this trial show that 8 weeks of Perfectil® Twin Serum use provide beneficial effect on skin radiance and skin surface relief (wrinkle depth). The action of the bi-phasic product may have a positive effect on the immediate penetration of the product which should be evaluated through the further studies. Furthermore, the ingredients seem to restore the skin lipidic layer, which explains its protective effect during winter time.

Alopecia types, current and future treatment

There are diverse types of alopecia and each call for a specific treatment. Regrettably there is no curative solution to the problem of alopecia as most drugs target its management. The purpose of the review is to explore the different types of alopecia and how each affect hair appearance and growth. The review begins by describing hair structure and hair physiological changes during life progression. A detailed description of conventional medication prescribed for alopecia and associated adverse effects are also pronounced in this review. Both approved (minoxidil and finasteride) and unapproved medications indicated for the condition are discussed to expose voids, which need to be filled by future drug development. The review also discusses the prospective future therapies of alopecia as directed by current research and technological advancement.