Aim. To assess resting energy expenditure (REE) in the early phase of acute severe pancreatitis. Materials and methods. Prospective, single-center, cohort study. Inclusion criteria: diagnosis of acute pancreatitis and presence of at least one predictor of severe course. REE was assessed using indirect calorimetry. A cohort of patients with a severe course was identified, in which four groups were formed: the first group included measurements performed on the first, third and fifth days, the second one – only on the first day, the third group – on the third day, and the fourth one – on the fifth day from the moment of admission into the intensive care unit in the early phase of acute severe pancreatitis. Statistical processing of the material was carried out using the SPSS software package. Results. REE fluctuations in the early phase of acute severe pancreatitis are statistically significant (p < 0.001). The maximum values fall on the first day 2690 (1990; 3100) kcal/day, the minimum values 2100 (1850; 2500) kcal/day – on the fifth day, from the moment of admission into the intensive care unit. When recalculating the REE for the patient’s weight, statistically significant differences were obtained in the compared groups (p < 0.001), with the maximum values on the first day of 30.24 [27.58-32.91] kcal/kg/day and the minimum values 24.37 (20, 91; 29.28) kcal/kg/day on the fifth day. Conclusions. In the early phase of acute severe pancreatitis, REE has statistically significant fluctuations with a maximum on the first day. The recommended amount of food in the first 3 days should not exceed 21 kcal/kg/day, and then 25 kcal/kg/day.
Longitudinal profiles of resting energy metabolism of adult covid-19 patients in intensive care
