The National Institute for Health and Care Excellence (NICE) Guidance on Bladder Cancer; a Step in the Right Direction?

2017 ◽  
Vol 29 (6) ◽  
pp. 344-347 ◽  
Author(s):  
S. Trainor ◽  
A. Choudhury ◽  
R. Huddart ◽  
A.E. Kiltie ◽  
R. Kockelbergh ◽  
...  
2019 ◽  
Vol 37 (7_suppl) ◽  
pp. 111-111
Author(s):  
Kotaro Obayashi

111 Background: Although previous studies have reported that the incidence of metachronous bladder cancer (MBC) is not significantly different after brachytherapy (BT) compared to radical prostatectomy (RP), few studies have reported differences in the pathological features (PF) of MBC between them. This study was conducted to clarify differences in the incidence and PF of MBC between BT and RP in our hospital. Methods: We reviewed 504 patients treated with BT and 471 referred patients treated with RP from 2006 to 2017 in our hospital. We checked the incidence of MBC in all patients and examined the PF including the tumor number, location within the bladder, histology, and time from BT or RP to the occurrence. The chi-square test and Mann-Whitney U test were performed to analyze the differences between the two groups. Results: After a median follow-up time of 66 months, a total of 8 cases of BC occurred in the BT group (1.6 %) and 5 in the RP group (1.1 %). The median time from initial treatment to the occurrence of MBC was 56 months (12-121) in BT and 71 months (4-126) in RP (p = 0.622). Average tumor number was not significantly different (BT:1.38, RP: 2.2, p = 0.265). The incidence of MBC in each location within the bladder for BT vs. RP was 4 vs 0 in the right wall, 3 vs 0 in the left wall, 0 vs 3 in the posterior wall, 0 vs 2 in the dome, and 1 vs 0 in the trigone. The incidence in the lateral wall was significantly higher in BT than in RP (p = 0.00466). There were 3 muscle-invasive cases in BT and 1 case in RP (p = 1.00). High-grade urothelial cancer occurred more in BT 8 than in RP 1 (p = 0.00699). Conclusions: The risk of MBC after BT appeared to be equivalent to patients after RP. MBC after BT occurred more in the lateral wall with worse PF compared to those after RP.


2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Yozo Mitsui ◽  
Naoko Arichi ◽  
Keita Inoue ◽  
Miho Hiraki ◽  
Shigenobu Nakamura ◽  
...  

Bladder cancer is the second most common genitourinary malignancy and has variable metastatic potential; however, choroidal and cutaneous metastases are extremely rare. Generally, a patient with these uncommon metastases has a very poor prognosis. We present a bladder cancer patient with a visual disorder in the right eye and multiple nodules on head and lower abdomen that developed 17 months after a radical cystectomy. These symptoms were determined to be caused by choroidal and cutaneous metastasis of bladder cancer. Although two cycles of combination chemotherapy were performed, the patient died 5 months after diagnosis of multiple metastases.


2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
S. Washino ◽  
M. Hirai ◽  
A. Matsuzaki ◽  
Y. Kobayashi

Isolated adrenal metastasis of bladder cancer, particularly the bilateral, is quite rare. Systemic chemotherapy is the treatment of choice for metastatic urothelial carcinoma. However, despite initially promising response rates of approximately 45%–71%, most tumors eventually show progression, and the median survival time following chemotherapy regimen is approximately 14-15 months. Recently, favorable results of surgery for metastatic urothelial carcinoma have been reported. Here, we report a rare case of asynchronous metastasis of bladder cancer to the bilateral adrenal glands with long-term survival after bilateral adrenalectomy. A 69-year-old man underwent radical cystoprostatectomy and ileal conduit urinary diversion for invasive bladder cancer. Ten months later, left adrenalectomy was performed for a left adrenal tumor, revealing metastatic urothelial carcinoma. After adjuvant chemotherapy, a tumor in the right adrenal gland was detected. Right adrenalectomy was done, and the tumor was also found to be metastatic urothelial carcinoma. The patient had an uneventful recovery after starting steroid replacement therapy. Three years later, he was doing well and had no evidence of recurrence. Adrenalectomy for isolated adrenal metastasis of urothelial carcinoma may be a reasonable option, even if such metastases are bilateral.


BMC Urology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xi Tu ◽  
Neng Zhang ◽  
Xiyao Zhuang ◽  
Shulian Chen ◽  
Xu Luo

Abstract Background Nonfunctional bladder paragangliomas is a rare urological disease. It may present clinical, radiology and pathological features similar to bladder cancer, Only scarce reports have been reported. Urologist must identify this generally benign neuroendocrine neoplasm to avoid misdiagnosis. Case presentation A 62-year-old female presented the outpatient department of our hospital with the symptoms of stomachache, frequent micturition, and urination pain for 20 days. Diagnosed with high blood pressure 1 year ago, administered Amlodipine besylate tablets 5 mg po qd occasionally, did not check blood pressure; denied any tumor observation in the family history. Color ultrasound of the urinary system showed a 38 mm × 34 mm hypoechoic mass on the right side of the bladder, CDFI: in the masses, blood supply was sufficient. Cystoscope showed bladder occupying lesion. Biopsy diagnosis: papillary polypoid cystitis was suspected as a malignant change (Fig. 3a). Then, the patient was admitted to our urological department. Further, computer tomography urography considered bladder cancer. Cystoscopy and biopsy failed to define the nature of the lesions in our outpatient department, which prompted a transurethral resection of the bladder tumor. histopathological and immunohistochemical results were diagnosed as bladder paragangliomas. For the reason, the tumor was removed by partial resection of the bladder. The postoperative recovery and follow-up were uneventful. Conclusions Nonfunctional bladder paragangliomas are occasionally found on imaging studies with the symptoms of urinary tract infection or/and intermittent painless hematuria. It may present clinical, radiology and pathological features similar to bladder cancer, so knowledge of this generally benign neuroendocrine neoplasm is of great importance to avoid misdiagnosis. It should be accompanied by the clinical and pathological characteristics of the patient and image changes. Partial resection of the bladder can effectively treat this disease.


1938 ◽  
Vol 34 (2) ◽  
pp. 203-205
Author(s):  
N. Kh. Sitdykov

Malignant neoplasms of the kidney are uncommon. According to German statistics, there are less than 1% of malignant kidney tumors per 100,000 autopsies. Ravasini found only 22 cases of malignant neoplasms of the kidneys and adrenal glands at 10,034 autopsies. In Lenequin's statistics for 10 years, out of 796 cancers, only one case of kidney cancer is indicated. According to Davydovsky's statistics, out of 2765 cases of malignant neoplasms, only 31 cases are in the kidneys.


2020 ◽  
Vol 13 (4) ◽  
pp. 24-29
Author(s):  
A.Yu. Pavlov ◽  
◽  
A.G. Dzidzaria ◽  
I.B. Kravtsov ◽  
A.D. Tsybulsky ◽  
...  

Introduction. According to autopsies, the frequency of unilateral kidney dystopia ranges from 1:660 to 1: 1000, with an average of 1:800 newborns, and lumbar dystopia is more common, mainly in boys. The left kidney is dystopian more often than the right. Bilateral dystopia is rare. In the structure of cancer incidence in the Russian population, bladder cancer ranks 9th among men and 17th among women. When analyzing the literature data, we did not find any recommendations for methods of urine derivation in patients with diagnosed bladder cancer in pelvic kidney dystopia. Materials and methods. Clinical case. A patient with a diagnosis of bladder cancer сT3bN0M0G1 associated with concomitant abnormality of the kidneys and urinary tract (pelvic kidney dystopia with shortening of the ureters) was admitted to the Department of oncourology of the Federal state budgetary institution RSCRR. The decision was made on the implementation of laparoscopic radical contractattachments, with an attempt of derivation of urine (formation ureteroileostomy) by Bricker. Intraoperatively: given the short length of the ureters, the location of the kidneys, it was decided to impose an end-to-end anastomosis of the ileoconduit with the pelvis of the right kidney, ureteroileoanastomosis end-to-side on the left. Based on the results of histological examination, the final clinical diagnosis was made: рТ2bN1М0G1R-. Results. 3 months after surgical treatment, no complications were observed, according to control studies, both anastomoses are passable. The planned adjuvant pоlichemotherapy (PCT) has been completed. There are no data for disease progression in the control examination. Conclusion. The method of urine removal is determined intraoperatively. In this patient, the condition and length of the right ureter did not allow performing classical ureteroileoanastomosis (end-to-end), and therefore pyeloileoanastomosis was performed on the right. On the left, the length of the ureter made it possible to perform end-to-side ureteroileoanastomosis, but only if the ileoconduit was removed to the left side.


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