Optimized production of antibacterial copper oxide nanoparticles in a microwave-assisted synthesis reaction using response surface methodology

2019 ◽  
Vol 573 ◽  
pp. 170-178 ◽  
Author(s):  
Shishir V. Kumar ◽  
Adarsh P. Bafana ◽  
Prasad Pawar ◽  
Meghana Faltane ◽  
Ashiqur Rahman ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Copper Oxide ◽  
Response Surface ◽  
Copper Oxide Nanoparticles ◽  
Microwave Assisted Synthesis ◽  
Oxide Nanoparticles ◽  
Synthesis Reaction ◽  
Microwave Assisted

Response surface methodology for the removal of nitrate ions by adsorption onto copper oxide nanoparticles

2020 ◽  
pp. 129686
Author(s):  
Somayeh Rahdar ◽  
Kaushik Pal ◽  
Leili Mohammadi ◽  
Abbas Rahdar ◽  
Yassman Goharniya ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Copper Oxide ◽  
Response Surface ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Nitrate Ions

scholarly journals Statistical Optimization of Copper Oxide Nanoparticles Using Response Surface Methodology and Box–Behnken Design Towards In Vitro and In Vivo Toxicity Assessment

2020 ◽  
Vol 11 (3) ◽  
pp. 10027-10039
Keyword(s):  
Response Surface Methodology ◽  
Copper Oxide ◽  
Response Surface ◽  
Copper Oxide Nanoparticles ◽  
Toxicity Assessment ◽  
P Value ◽  
Oxide Nanoparticles ◽  
Box Behnken Design

The current study focusses on the optimization of Copper oxide nanoparticles (CuO NPs) biosynthesis with Alternanthera sessilis (L.) extract using response surface methodology (RSM). The effect of time, pH, and extract to metal concentration ratio on the yield of synthesized nanoparticles (NPs) were estimated using Box–Behnken design. The influence of each of the parameters, as mentioned earlier, was determined by synthesizing nanoparticles under different conditions. A total of 29 experimental runs were carried out to estimate the crucial parameters. Extract to the metal ratio was found to be the vital parameter for yield optimization based on the p-values (p-value < 0.05). The physicochemical property of NPs, like size, was estimated to be in the range of 10-20 nm. In zebrafish, 48 hpf and 72 hpf were measured at 90 µM to reduce dysfunction and mortality during organ development. These results can have a valuable impact on eco-toxicological effects.

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