microwave assisted synthesis
Recently Published Documents





Molecules ◽  
2022 ◽  
Vol 27 (2) ◽  
pp. 337
Adam Chyzy ◽  
Damian Pawelski ◽  
Vladyslav Vivcharenko ◽  
Agata Przekora ◽  
Michael Bratychak ◽  

In this study, well-known oligomers containing ethyl methacrylate (EMA) and glycidyl methacrylate (GMA) components for the synthesis of the oligomeric network [P(EMA)-co-(GMA)] were used. In order to change the hydrophobic character of the [P(EMA)-co-(GMA)] to a more hydrophilic one, the oligomeric chain was functionalized with ethanolamine, xylitol (Xyl), and L-ornithine. The oligomeric materials were characterized by nuclear magnetic resonance and Fourier transform infrared spectroscopy, scanning electron microscopy, and differential thermogravimetric analysis. In the final stage, thanks to the large amount of -OH groups, it was possible to obtain a three-dimensional hydrogel (HG) network. The HGs were used as a matrix for the immobilization of methylene blue, which was chosen as a model compound of active substances, the release of which from the matrix was examined using spectrophotometric detection. The cytotoxic test was performed using fluid extracts of the HGs and human skin fibroblasts. The cell culture experiment showed that only [P(EMA)-co-(GMA)] and [P(EMA)-co-(GMA)]-Xyl have the potential to be used in biomedical applications. The studies revealed that the obtained HGs were porous and non-cytotoxic, which gives them the opportunity to possess great potential for use as an oligomeric network for drug reservoirs in in vitro application.

2022 ◽  
Demet Taşdemir ◽  
Ayşegül Karaküçük-İyidoğan ◽  
Yasemin Saygideger ◽  
EMİNE Elçin Emre ◽  
Tuğba Taşkın-Tok ◽  

Hypoxia-inducible factors (HIF), one of the targeted treatment strategies with a rising promise in lung cancer, are known to play a role in tumor growth and other oncogenic properties in...

2022 ◽  
Vol 890 ◽  
pp. 161825
Harikrishnan Ravichandran ◽  
Baskaran Irusan ◽  
Sathyaseelan Balaraman ◽  
Mani Govindasamy ◽  
Senthilnathan Krishnamoorthy ◽  

2022 ◽  
Chen Chen ◽  
Jiamei Zhao ◽  
Dong Guo ◽  
Keyu Duan ◽  
Yongqiang Wang ◽  

CaTiO3 is considered to be one of the most potential catalysts for the degradation of organic pollutants, but its application is limited due to the wide band gap and low...

Sign in / Sign up

Export Citation Format

Share Document