Efficient Synthesis of POSS Based Amphiphilic Nanoparticles via Thiol-ene "Click" Reaction to Improve Foam Stability

2021 ◽  
pp. 127803
Author(s):  
Feng Jiang ◽  
Yuhong Chen ◽  
Zhuangjie Ye ◽  
Shishi Pang ◽  
Bin Xu
Keyword(s):  
Click Reaction ◽  
Foam Stability ◽  
Efficient Synthesis ◽  
Amphiphilic Nanoparticles

Regioselective synthesis of multisubstituted 1,2,3-triazoles: moving beyond the copper-catalyzed azide–alkyne cycloaddition

2016 ◽  
Vol 52 (99) ◽  
pp. 14188-14199 ◽  
Author(s):  
Fang Wei ◽  
Weiguo Wang ◽  
Yudao Ma ◽  
Chen-Ho Tung ◽  
Zhenghu Xu
Keyword(s):  
Recent Progress ◽  
Click Reaction ◽  
Regioselective Synthesis ◽  
Efficient Synthesis ◽  
Feature Article

Copper(i)-catalyzed azide–alkyne cycloaddition (CuAAC) provides an efficient synthesis of 1,4-disubstituted 1,2,3-triazoles. This feature article highlights the recent progress on the regisoselective synthesis of multisubstituted 1,2,3-triazoles, which current click reaction (CuAAC) is unable to do.

scholarly journals Fused Tetrazoles as Azide Surrogates in Click Reaction: Efficient Synthesis of N-Heterocycle-Substituted 1,2,3-Triazoles

2010 ◽  
Vol 12 (9) ◽  
pp. 2166-2169 ◽  
Author(s):  
Buddhadeb Chattopadhyay ◽  
Claudia I. Rivera Vera ◽  
Stepan Chuprakov ◽  
Vladimir Gevorgyan
Keyword(s):  
Click Reaction ◽  
Efficient Synthesis

scholarly journals Synthesis of Carvone-Derived 1,2,3-Triazoles Study of Their Antioxidant Properties and Interaction with Bovine Serum Albumin

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2991 ◽  
Author(s):  
Armen Galstyan ◽  
Armen Martiryan ◽  
Karine Grigoryan ◽  
Armine Ghazaryan ◽  
Melanya Samvelyan ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Serum Albumin ◽  
Hydrophobic Interactions ◽  
Click Reaction ◽  
Antioxidant Properties ◽  
Synthetic Route ◽  
Efficient Synthesis ◽  
Solubility In Water ◽  
Reversible Binding ◽  
High Antioxidant Activity

Natural L-carvone was utilized as a starting material for an efficient synthesis of some terpenyl-derived 1,2,3-triazoles. Chlorination of carvone, followed by nucleophilic substitution with sodium azide resulted in the preparation of 10-azidocarvone. Subsequent CuAAC click reaction with propargylated derivatives provided an efficient synthetic route to a set of terpenyl-derived conjugates with increased solubility in water. All investigated compounds exhibit high antioxidant activity, which is comparable with that of vitamin C. It was also found that serum albumin and the terpenyl-1,2,3-triazoles hybrids spontaneously undergo reversible binding driven by hydrophobic interactions, suggesting that serum albumin can transport the target triazoles.

Simple and efficient synthesis of $$5'$$ 5 ′ -aryl- $$5'$$ 5 ′ -deoxyguanosine analogs by azide-alkyne click reaction and their antileishmanial activities

2016 ◽  
Vol 20 (2) ◽  
pp. 507-519 ◽  
Author(s):  
Pierre Daligaux ◽  
Sébastien Pomel ◽  
Karine Leblanc ◽  
Philippe M. Loiseau ◽  
Christian Cavé
Keyword(s):  
Click Reaction ◽  
Efficient Synthesis ◽  
Antileishmanial Activities

Efficient synthesis of novel β-sitosterol scaffolds containing 1,2,3-triazole via copper(I)-catalyzed click reaction under microwave irradiation

2017 ◽  
Vol 72 (10) ◽  
pp. 717-724 ◽  
Author(s):  
Jin-Wei Yuan ◽  
Ling-Bo Qu
Keyword(s):  
Microwave Irradiation ◽  
Click Reaction ◽  
Reaction Times ◽  
Cycloaddition Reactions ◽  
Efficient Synthesis ◽  
High Yields ◽  
Work Up ◽  
Derivatives Of

AbstractIn this work, new derivatives of the β-sitosterol scaffolds containing 1,2,3-triazole are prepared by the reaction of β-sitosterol with aromatic alkynes via copper(I)-catalyzed azide-alkyne cycloaddition reactions under microwave irradiation. The reaction has several advantages including high yields, short reaction times, and a simple work-up procedure.

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