Improving antibody drug development using bionanotechnology

Current Opinion in Biotechnology ◽

10.1016/j.copbio.2021.10.027 ◽

2022 ◽

Vol 74 ◽

pp. 137-145

Author(s):

Emily K Makowski ◽

John S Schardt ◽

Peter M Tessier

Keyword(s):

Drug Development ◽

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Mass Spectrometry of Antibody–Drug Conjugates in Plasma and Tissue in Drug Development

Characterization of Protein Therapeutics using Mass Spectrometry ◽

10.1007/978-1-4419-7862-2_7 ◽

2013 ◽

pp. 279-304 ◽

Author(s):

Surinder Kaur ◽

Keyang Xu ◽

Ola Saad ◽

Luna Liu ◽

Tim Slattery ◽

...

Keyword(s):

Mass Spectrometry ◽

Drug Development ◽

Antibody Drug Conjugates ◽

Drug Conjugates ◽

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Abstract 5391: Antibody-drug conjugates in oncology drug development: Examining approaches to set the first-in-human dose

10.1158/1538-7445.am2012-5391 ◽

2012 ◽

Author(s):

Nadine N. Bewry

Keyword(s):

Drug Development ◽

Antibody Drug Conjugates ◽

Drug Conjugates ◽

Oncology Drug ◽

Oncology Drug Development ◽

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Mass Spectrometry-Based Methodologies for Pharmacokinetic Characterization of Antibody Drug Conjugate Candidates During Drug Development

Protein Analysis using Mass Spectrometry ◽

10.1002/9781119371779.ch14 ◽

2017 ◽

pp. 183-201 ◽

Author(s):

Yongjun Xue ◽

Priya Sriraman ◽

Matthew V. Myers ◽

Xiaomin Wang ◽

Jian Chen ◽

...

Keyword(s):

Mass Spectrometry ◽

Drug Development ◽

Antibody Drug Conjugate ◽

Drug Conjugate ◽

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Book Review: Antibody-Drug Conjugates: Fundamentals, Drug Development, and Clinical Outcomes to Target Cancer

Frontiers in Pharmacology ◽

10.3389/fphar.2017.00771 ◽

2017 ◽

Vol 8 ◽

Author(s):

Dipesh Dhakal ◽

Yogesh Dhakal ◽

Jae K. Sohng

Keyword(s):

Drug Development ◽

Clinical Outcomes ◽

Antibody Drug Conjugates ◽

Drug Conjugates ◽

Antibody Drug ◽

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Abstract 2954: Humanized CCR8 mouse model provides a translational tool for anti-human CCR8 antibody drug development

10.1158/1538-7445.am2021-2954 ◽

2021 ◽

Author(s):

Linlin Wang ◽

Chengzhang Shang ◽

Jing Zhang ◽

Yichao Chen ◽

Leila Kokabee ◽

...

Keyword(s):

Mouse Model ◽

Drug Development ◽

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Overcoming Challenges of Implementing Closed System Transfer Device Clinical In-Use Compatibility Testing for Drug Development of Antibody Drug Conjugates

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2019.07.021 ◽

2020 ◽

Vol 109 (1) ◽

pp. 761-768 ◽

Author(s):

Frankie Petoskey ◽

Stanley C. Kwok ◽

William Jackson ◽

Shan Jiang

Keyword(s):

Drug Development ◽

Closed System ◽

Antibody Drug Conjugates ◽

Drug Conjugates ◽

Antibody Drug ◽

Transfer Device

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DRUG DEVELOPMENT ADC Therapeutics will focus on antibody-drug conjugates for cancer

Chemical & Engineering News ◽

10.1021/cen-09014-notw5 ◽

2012 ◽

Vol 90 (14) ◽

pp. 7

Keyword(s):

Drug Development ◽

Antibody Drug Conjugates ◽

Drug Conjugates ◽

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Abstract 2343: Comprehensive evaluation of antibody-drug conjugate targets for drug development across tumor types: Analysis from TCGA

10.1158/1538-7445.am2018-2343 ◽

2018 ◽

Author(s):

Roman Groisberg ◽

Jason Rosznik ◽

Funda Meric-Bernstam ◽

Vivek Subbiah

Keyword(s):

Drug Development ◽

Comprehensive Evaluation ◽

Antibody Drug Conjugate ◽

Drug Conjugate ◽

Tumor Types ◽

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HER2-Overexpressing/Amplified Breast Cancer as a Testing Ground for Antibody–Drug Conjugate Drug Development in Solid Tumors

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-18-1976 ◽

2019 ◽

Vol 26 (4) ◽

pp. 775-786 ◽

Author(s):

Mark D. Pegram ◽

David Miles ◽

C. Kimberly Tsui ◽

Yu Zong

Keyword(s):

Breast Cancer ◽

Drug Development ◽

Solid Tumors ◽

Antibody Drug Conjugate ◽

Drug Conjugate ◽

Testing Ground ◽

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Antibody–drug conjugate drug development: where are the challenges?

Bioanalysis ◽

10.4155/bio.13.104 ◽

2013 ◽

Vol 5 (12) ◽

pp. 1467-1469

Author(s):

Laura Wright ◽

Sharon Baughman ◽

Ashleigh Wake

Keyword(s):

Drug Development ◽

Antibody Drug Conjugate ◽

Drug Conjugate ◽

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