scholarly journals A Noradrenergic Mechanism Functions to Couple Motor Behavior with Arousal State

2013 ◽  
Vol 23 (18) ◽  
pp. 1719-1725 ◽  
Author(s):  
Christian R. Burgess ◽  
John H. Peever
2010 ◽  
Vol 24 (2) ◽  
pp. 76-82 ◽  
Author(s):  
Martin M. Monti ◽  
Adrian M. Owen

Recent evidence has suggested that functional neuroimaging may play a crucial role in assessing residual cognition and awareness in brain injury survivors. In particular, brain insults that compromise the patient’s ability to produce motor output may render standard clinical testing ineffective. Indeed, if patients were aware but unable to signal so via motor behavior, they would be impossible to distinguish, at the bedside, from vegetative patients. Considering the alarming rate with which minimally conscious patients are misdiagnosed as vegetative, and the severe medical, legal, and ethical implications of such decisions, novel tools are urgently required to complement current clinical-assessment protocols. Functional neuroimaging may be particularly suited to this aim by providing a window on brain function without requiring patients to produce any motor output. Specifically, the possibility of detecting signs of willful behavior by directly observing brain activity (i.e., “brain behavior”), rather than motoric output, allows this approach to reach beyond what is observable at the bedside with standard clinical assessments. In addition, several neuroimaging studies have already highlighted neuroimaging protocols that can distinguish automatic brain responses from willful brain activity, making it possible to employ willful brain activations as an index of awareness. Certainly, neuroimaging in patient populations faces some theoretical and experimental difficulties, but willful, task-dependent, brain activation may be the only way to discriminate the conscious, but immobile, patient from the unconscious one.


1981 ◽  
Vol 26 (4) ◽  
pp. 258-259
Author(s):  
Jack A. Adams
Keyword(s):  

1981 ◽  
Vol 26 (11) ◽  
pp. 884-884
Author(s):  
Waneen Wyrick Spirduso
Keyword(s):  

1983 ◽  
Vol 28 (10) ◽  
pp. 785-786
Author(s):  
Beth Kerr
Keyword(s):  

1956 ◽  
Author(s):  
Philip J. Bersh ◽  
Joseph M. Notterman ◽  
William N. Schoenfeld

Sign in / Sign up

Export Citation Format

Share Document