scholarly journals Individual associations of adolescent alcohol use disorder versus cannabis use disorder symptoms in neural prediction error signaling and the response to novelty

2021 ◽  
pp. 100944
Author(s):  
Joseph Aloi ◽  
Kathleen I. Crum ◽  
Karina S. Blair ◽  
Ru Zhang ◽  
Johannah Bashford-Largo ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Prediction Error ◽  
Alcohol Use Disorder ◽  
Cannabis Use ◽  
Cannabis Use Disorder ◽  
Adolescent Alcohol Use ◽  
Adolescent Alcohol

scholarly journals Accelerated alcohol use across adolescence predicts early adult symptoms of alcohol use disorder via reward-related neural function

2018 ◽  
Vol 49 (4) ◽  
pp. 675-684 ◽  
Author(s):  
Rebecca Waller ◽  
Laura Murray ◽  
Daniel S. Shaw ◽  
Erika E. Forbes ◽  
Luke W. Hyde
Keyword(s):  
Alcohol Use ◽  
Low Income ◽  
Alcohol Use Disorder ◽  
Early Adulthood ◽  
Region Of Interest ◽  
Neural Function ◽  
Psychiatric Interview ◽  
Adolescent Alcohol Use ◽  
Adolescent Alcohol ◽  
Reward Anticipation

AbstractBackgroundAlcohol use is commonly initiated during adolescence, with earlier onset known to increase the risk for alcohol use disorder (AUD). Altered function in neural reward circuitry is thought to increase the risk for AUD. To test the hypothesis that adolescent alcohol misuse primes the brain for alcohol-related psychopathology in early adulthood, we examined whether adolescent alcohol consumption rates predicted reward responsivity in the ventral striatum (VS), and in turn, AUD symptoms in adulthood.MethodsA total of 139 low income, racially diverse urban males reported on their alcohol use at ages 11, 12, 15, and 17; completed self-reports of personality, psychiatric interviews, and a functional magnetic resonance imaging (fMRI) scan at age 20; and completed a psychiatric interview at age 22. We measured adolescent alcohol use trajectories using latent growth curve modeling and measured neural responses to monetary reward using a VS region of interest. We tested indirect effects of adolescent alcohol use on AUD symptoms at age 22 via VS reward-related reactivity at age 20.ResultsGreater acceleration in adolescent alcohol use predicted increased VS response during reward anticipation at age 20. VS reactivity to reward anticipation at age 20 predicted AUD symptoms at age 22, over and above concurrent symptoms. Accelerated adolescent alcohol use predicted AUD symptoms in early adulthood via greater VS reactivity to reward anticipation.ConclusionsProspective findings support a pathway through which adolescent alcohol use increases the risk for AUD in early adulthood by impacting reward-related neural functioning. These results highlight increased VS reward-related reactivity as a biomarker for AUD vulnerability.

scholarly journals Mother and Father Prescription Opioid Misuse, Alcohol Use Disorder, and Parent Knowledge in Pathways to Adolescent Alcohol Use

2020 ◽  
Vol 49 (8) ◽  
pp. 1663-1673
Author(s):  
Kit K. Elam ◽  
Ariel Sternberg ◽  
Jack T. Waddell ◽  
Austin J. Blake ◽  
Laurie Chassin
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Prescription Opioid ◽  
Opioid Misuse ◽  
Parent Knowledge ◽  
Adolescent Alcohol Use ◽  
Adolescent Alcohol ◽  
Prescription Opioid Misuse

scholarly journals Delinquency as a mediator of the relation between negative affectivity and adolescent alcohol use disorder

2007 ◽  
Vol 32 (12) ◽  
pp. 2747-2765 ◽  
Author(s):  
Gavin D. Shoal ◽  
Lauren C. Gudonis ◽  
Peter R. Giancola ◽  
Ralph E. Tarter
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Negative Affectivity ◽  
Adolescent Alcohol Use ◽  
Adolescent Alcohol

scholarly journals Alcohol use disorder and cannabis use disorder symptomatology in adolescents are differentially related to dysfunction in brain regions supporting face processing

2019 ◽  
Vol 292 ◽  
pp. 62-71 ◽  
Author(s):  
Emily K. Leiker ◽  
Harma Meffert ◽  
Laura C. Thornton ◽  
Brittany K. Taylor ◽  
Joseph Aloi ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Face Processing ◽  
Alcohol Use Disorder ◽  
Brain Regions ◽  
Cannabis Use ◽  
Cannabis Use Disorder

Psychosocial and health problems associated with alcohol use disorder and cannabis use disorder in U.S. adults

2021 ◽  
pp. 109137
Author(s):  
Sarah Gutkind ◽  
David S. Fink ◽  
Dvora Shmulewitz ◽  
Malka Stohl ◽  
Deborah Hasin
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Health Problems ◽  
Cannabis Use ◽  
Cannabis Use Disorder

scholarly journals Sleep and circadian contributions to adolescent alcohol use disorder

Alcohol ◽  
2015 ◽  
Vol 49 (4) ◽  
pp. 377-387 ◽  
Author(s):  
Brant P. Hasler ◽  
Adriane M. Soehner ◽  
Duncan B. Clark
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Adolescent Alcohol Use ◽  
Adolescent Alcohol

Difficult Temperament, Parental Relationships, and Adolescent Alcohol Use Disorder Symptoms

2000 ◽  
Vol 10 (1) ◽  
pp. 69-86 ◽  
Author(s):  
Bryan D. Neighbors ◽  
Duncan B. Clark ◽  
John E. Donovan ◽  
Gene H. Brody
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Parental Relationships ◽  
Adolescent Alcohol Use ◽  
Adolescent Alcohol
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